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2018, Number 4

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Rev Med MD 2018; 9.10 (4)

RDW as an independent risk factor for mortality in nosocomial pneumonia

Lambraño-Castillo D, Lambraño-Castillo J, Cruz-Domínguez MP

Language: Spanish
References: 24
Page: 311-316
PDF size: 631.37 Kb.


ABSTRACT

Introduction. Nosocomial pneumonia (NP) it's one of the main infectious causes of death. Prognosis is an important part of the management of patients with NP, an elevated RDW is associated with greater mortality. Our objective was to calculate the association between RDW ›14.5% at 72 hrs from the diagnosis of NP as an independent risk factor for mortality.
Material and Methods. We did a retrospective analysis of patients with diagnosis of NP, with RDW measurements at diagnosis and at 72 hours, the disease severity was determined based on the APACHE II score. The primary objective was to calculate the risk that the RDW ›14.5% at 72 hrs from diagnosis independently confers on patients with NP.
Results. A total of 88 patients were included, the RDW ›14.5% were more common in the case group 32 (71.1%) vs. control group 16 (37.2%), (p= 0,001, IC 95 %). 72 patients were considered to have complicated NP (81.1%). Patients in the case group were more likely to have an APACHE II score equal or greater than 18 points 31 (68.9%), and were more likely to have antibiotic treatment failure 34 (75,6 %) (p= 0,001, IC 95 %). The OR for RDW ›14.5% was 4.16 (IC 95 % 1, 70 - 10, 14 p= 0,001), and was considered an independent risk factor for mortality.
Discussion. A RDW ›14.5% measured 72 hour from the diagnosis of NP was associated with mortality as an independent risk factor.


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