Clinical and demographic description of HIV/HCV co-infected patients in central Mexico

Luis Esteban Ramírez-González; Alicia Piñeirua-Menendez; Florentino Badial-Hernández; Juan Francisco Sánchez-Ávila; Areli Pérez-Carrizosa; Antonio Camiro-Zúñiga; Emmanuel Simental-Aldaba; Irwin Zamora-Tapia; Karen Aranza Marañón-Solorio; Juan Gerardo Sierra-Madero

2018, Number 4

Rev Med MD 2018; 9.10 (4)

Clinical and demographic description of HIV/HCV co-infected patients in central Mexico

Ramírez-González LE, Piñeirua-Menendez A, Badial-Hernández F, Sánchez-Ávila Jf, Pérez-Carrizosa A, Camiro-Zúñiga A, Simental-Aldaba E, Zamora-Tapia I, Marañón-Solorio KA, Sierra-Madero JG

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ABSTRACT

Introduction. Worldwide incidence of hepatitis C (HCV) in the HIV infected population have been increasing in the last decades. There are few data related to demographic characteristics in the Latin American countries and risk factors associated with transmission.
Material and Methods. Between 2016 and 2018 was conducted a transversal descriptive study of the HCV co-infected population at three reference centers for people living with HIV/AIDS. The included participants were HIV positive with HCV confirmed co-infection. The HCV serostatus was assessed by viral load. Questionnaires covering socio-demographic data; sexual behavior and history of drug use was applied to all the participants.
Results. From a population of 14,000 patients attending to the HIV reference centres at mexico city we recruited 195 with HIV/HCV co-infection. Male population were 185 (94.9%), median age 38.5 [IQR] (25-3-51-8). The most frequent genotypes were 1a (n=71, 36.4%), 1b and 4, (n=6, 12%, each one). Sage of fibrosis was determined by transient elastography, most patients with low stage fibrosis F0-F1 (n=133, 76.9%). Traditional risk factors reported in co-infected population were history of tattoo reported by 41.2% of participants, history of piercing (56%), history of transfusion (12.3%, 7.2% reported transfusion before year 1994, 2.6% repot history of I.V. drug use, 114 (58.4%) reported history of unprotected receptive anal intercourse.
Discussion. Reported data suggest that traditional risk factors might be not the only routes of transmission of HCV in the HIV population further studies are needed to asses risk factors related to transmission.

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