2018, Number 4
<< Back Next >>
Med Crit 2018; 32 (4)
Base deficit versus carbon dioxide delta as a prognostic factor of complications in hemorrhagic shock
Ledezma RF, Solís ADA, Mendoza RM
Language: Spanish
References: 16
Page: 217-224
PDF size: 220.58 Kb.
ABSTRACT
Objective: Demonstrate that the baseline deficit is a better prognostic factor than the CO
2 delta to assess the complications of hemorrhagic shock.
Methodology: An observational, descriptive, analytical, longitudinal and retrospective study was performed. This study included all patients diagnosed with hemorrhagic shock during the period from January 2016 to May 2017, where 27 patients were collected. For the analysis of the results we used measures of central tendency, tests of significance, sensitivity and specificity of each one of the tests.
Results: It was observed that the sensitivity and specificity of the baseline and CO
2 delta deficits were 76% and 40% specificity compared to base deficit with 70% sensitivity and 50% specificity.
Conclusions: In this study, no statistically significant difference was found as a predictive factor between the CO
2 delta and the baseline deficit in the follow-up of the resuscitation of hemorrhagic shock. The two tests have good sensitivity, however they have little specificity, so in the management of resuscitation of hemorrhagic shock can not be used in isolation. Complications of hemorrhagic shock were acute lung injury, renal injury, and cardiovascular dysfunction.
REFERENCES
Jonhes AE, Jefrey AK. Rosen’s emergency medicine. Chapter 4 Shock, Vol 1, 7th ed. Elsevier. 2014. pp. 65-68.
Gerard MM, Christian VL, Federico E. Fisiopatología del choque hipovolémico. Bases fisiopatológicas del tratamiento. Medicina Intensiva. Cap. 17, p. 105.
Sebastián U. Clasificación del choque en cuatro modelos. Cuidado Intensivo de la teoría a la práctica. Green Book, Cap. 34, p. 356.
Ospina-Tascón GA, Umaña M, Bermúdez WF, Bautista-Rincón DF, Valencia JD, Madriñán HJ, et al. Can venous-to-arterial carbon dioxide differences reflect microcirculatory alterations in patients with septic shock? Intensive Care Med. 2016;42(2):211-221.
Mallat J, Lemyze M, Tronchon L, Vallet B, Thevenin D. Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock. World J Crit Care Med. 2016;5(1):47-56.
Ocelotl PR, Valle RJ, De Jesús BD, Cortés MJ, Herrera MB, Mendoza RM. Delta de CO2 como factor de riesgo de muerte en choque séptico. Rev Asoc Mex Med Crit Ter Intensiva. 2016;30(1):30-42.
Robin E, Futier E, Pires O, Fleyfel M, Tavernier B, Lebuffe G, et al. Central venous-to-arterial carbón dioxide difference as a prognotic tool in high risk surgical patients. Crit Care. 2015;13:227.
Bouglé A, Harrois A, Duranteau J. Resuscitative strategies in traumatic hemorrhagic shock. Ann Intensive Care. 2013;3(1):1.
Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med. 2004;350(22):2247-2256.
Sosa-García JO, Carrillo-Esper R. Coloides versus cristaloides. Un análisis basado en evidencia. Paciente en Estado Crítico. 2013;36(Supl. 1):S270-S272.
Richards JB, Wilcox SR. Diagnosis and management of shock. Emerg Med Pract. 2014;16(3):1-22; quiz 22-3.
Jacob M, Kumar P. The challenge in management of hemorrhagic shock in trauma. Med J Armed Forces India. 2014;70(2):163-169.
Díaza O, Yepesb MJ, Vilac M, García Gregorioc N., Plazac M. Errando. Hemorragia y transfusión masivas. Recomendaciones para la elaboración de un protocolo. Rev Esp Anestesiol Reanim. 2013;60(Supl. 1):73-85.
Mutschler M, Nienaber U, Brockamp T, Wafaisade A, Fabian T, Paffrath T, et al. Renaissance of base deficit for the initial assessment of trauma patients: a base deficit based classification for hypovolemic shock developed on data from 16,305 patients derived from the TraumaRegister DGU®. Crit Care. 2013;17(2):R42.
Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Enrique Fernández-ME. The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition. Critical Care. 2016;20:100.
Laverde SC, Correa RA, Joya HA. Lactate and base deficit in trauma: Prognostic value. Rev Colomb Anestesiol. 2014;42(1):60-64.