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2018, Number 2

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Anales de Radiología México 2018; 17 (2)

Preoperative sonographic assessment of axillary nodes in patients newly diagnosed with breast cancer

Zapata-Julián P, Garza-Montemayor M, Avendaño-Avalos DB

Language: Spanish
References: 27
Page: 85-92
PDF size: 214.80 Kb.


ABSTRACT

Intoducction: Breast cancer is one of the main causes of morbidity and mortality in the world, and Mexico is no exception. The most important prognostic factor in breast cancer is the status of axillary nodes.
Objectives: To study the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of axillary sonography, and a sonogram plus fine needle aspiration biopsy of the axillary nodes, for local and regional staging of breast cancer.
Material and Methods: This is a descriptive, retrospective, comparative, replicative and observational study. Patients diagnosed with breast cancer at the Centro de Imagen Diagnóstica de Cáncer de Mama del Hospital San José were included in the study from January 2010 to October 2016. Axillary ultrasound images were reclassified according to BNR morphological groups (Rostagno et al.). Sensitivity and specificity of sonography and sonography plus aspiration biopsy was established, assigning predictive values per morphological group compared to the gold standard (pathology) in axillary surgery (lymph node dissection or sentinel node).
Results: 227 patients were included. Axillary sonography and sonography plus biopsy showed 69.62% and 73.53% sensitivity, 64.19% and 80% specificity, 50.93% and 86.21% PPV and 79.83% and 64% NPV respectively. NPV in BRN-1 and BRN2 groups was 60.1% and 59.89% respectively. PPV of groups BRN-3, BRN-4 and BRN-5 was 34%, 55.7% and 91.67% respectively.
Conclusions: Axillary sonography for morphological assessment plus aspiration biopsy of abnormal axillary nodes in patients with breast cancer is an important tool for the preoperative evaluation of local and regional metastasis.


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