medigraphic.com
ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología

2018, Number 1

<< Back Next >>

Rev Latin Infect Pediatr 2018; 31 (1)

Falciparum malaria and severe thrombocytopenia

Castilla HNK, Bustos GÁ

Language: Spanish
References: 10
Page: 32-35
PDF size: 277.96 Kb.


ABSTRACT

Idiopathic immune thrombocytopenic purpura is the most frequent hemorrhagic disease in children. Among the thrombocytopenias associated with parasites, however, that induced by malaria is prevalent. We present the case of a three-year-old boy from an endemic area of malaria in Colombia, with Plasmodium falciparum malaria whose initial treatment was unknown, who consulted for relapse of his clinical picture, which was characterized by anemia, low parasitemia, persistence of gametocytes, bleeding and reticulocytosis. The manifestations of the disease were varied, but deep thrombocytopenia stood out. After ten days of hospital stay, a marked improvement was obtained, confirmed by the negativization of the hemoparasite and normalization of hemoglobin and platelet values.


REFERENCES

  1. Lacerda MV, Mourão MP, Coelho HC, Santos JB. Thrombocytopenia in malaria: who cares? Mem Inst Oswaldo Cruz. 2011; 106 Suppl 1: 52-63.

  2. Gupta NK, Bansal SB, Jain UC, Sahare K. Study of thrombocytopenia in patients of malaria. Trop Parasitol. 2013; 3 (1): 58-61.

  3. Meena KR, Kumar A. Thrombocytopenia in children with malaria: a study from tertiary care Hospital Delhi. India. IJSRP. 2013; 3 (8): 1-3.

  4. Lampah DA, Yeo TW, Malloy M, Kenangalem E, Douglas NM, Ronaldo D et al. Severe malarial thrombocytopenia: a risk factor for mortality in Papua, Indonesia. J Infect Dis. 2015; 211 (4): 623-634.

  5. Coelho HC, Lopes SC, Pimentel JP, Nogueira PA, Costa FT, Siqueira AM et al. Thrombocytopenia in Plasmodium vivax malaria is related to platelets phagocytosis. PLoS One. 2013; 8 (5): e63410.

  6. Moulin F, Lesage F, Legros AH, Maroga C, Moussavou A, Guyon P et al. Thrombocytopenia and Plasmodium falciparum malaria in children with different exposures. Arch Dis Child. 2003; 88 (6): 540-541.

  7. Saravu K, Docherla M, Vasudev A, Shastry BA. Thrombocytopenia in vivax and falciparum malaria: an observational study of 131 patients in Karnataka, India. Ann Trop Med Parasitol. 2011; 105 (8): 593-598.

  8. Manning L, Laman M, Law I, Bona C, Aipit S, Teine D et al. Features and prognosis of severe malaria caused by Plasmodium falciparum, Plasmodium vivax and mixed Plasmodium species in Papua New Guinean children. PLoS One. 2011; 6 (12): e29203.

  9. Kreil A, Wenisch C, Brittenham G, Looareesuwan S, Peck-Radosavljevic M. Thrombopoietin in Plasmodium falciparum malaria. Br J Haematol. 2000; 109 (3): 534-536.

  10. Elawad M, Jobran J, Duya A. Immunoglobulin therapy for severe thrombocytopenia complicating falciparum malaria. Trop Med Int Health. 1999; 4 (12): 812-813.




2020     |     www.medigraphic.com