Ignacio SJ, Emilio SL, Massó F, Paez A, Varela E, Rodríguez E, Montaño LF

Language: Spanish
References: 20
Page: 227-230
PDF size: 70.86 Kb.

ABSTRACT

The aim of this study was to evaluate the serum antibody concentration induced by natural exposure to Rubella virus, hepatitis B virus, and Haemophilus influenzae type b, in 12-14 year-old Mexican children of a very low socioeconomic background non immunized with the specific vaccines currently available. The 195 children, who were accompanying their mothers or a brother or sister to consultation for various reasons, were detected at the Paediatric Service Ambulatory Unit of Mexico’s City General Hospital. Eleven males and six females had a history of rubella, none of the children had suffered from hepatitis B or meningitis. Mean anti-Hib specific IgG antibody concentration was 10.17 ± 6.81 mg/mL but mean bactericidal activity of the sera was 0.44 ± 0.08 mg/mL versus 0.11 ± 0.05 mg/mL of sera obtained from HbOC immunized children. Mean anti-rubella specific IgG antibody concentration was 114.99 ± 71.07 mg/mL but 19% of the children had antibody levels below those considered protective. Only two children were HBsAb positive. Our results confirm the need for screening and application of vaccine to adolescents who did not receive them in their early infancy those that are now included in the national vaccine scheme.

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