2018, Number 3
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Rev Mex Pediatr 2018; 85 (3)
Moebius syndrome: a clinical case report
Canalejo-Saavedra V, Sierra-García R, Salinas-Meritú A
Language: Spanish
References: 15
Page: 102-105
PDF size: 240.23 Kb.
ABSTRACT
Introduction: Moebius syndrome is a congenital neurological
entity characterized by bilateral palsy of two cranial nerves,
the facial (VII) and external oculomotor (VI) or
abducens,
which manifests mainly by facial expression. This pathology
has an incidence of 1:10,000 births worldwide; there are no
clear statistics in Mexico.
Case presentation: We detected
a neonate patient with clinical characteristics compatible with
this syndrome, supported by the Ophthalmology Service.
The diagnosis was basically clinical and the management,
multidisciplinary.
Conclusions: Knowledge of this problem
can guide us to the diagnostic suspicion in a timely manner,
thus preventing complications and improving the quality of
life in language, facial expressiveness, craniofacial growth
and adaptability to the social environment.
REFERENCES
Palmer-Morales Y, Zárate-Márquez RE, Prince-Vélez R, González- Méndez R, Zamarripa-Sandoval TA, Verdugo-Salazar N et al. Síndrome de Moebius: informe de un caso clínico. Rev Med Inst Mex Seguro Soc. 2013; 51(5): 584-586.
Sixto FS, Ortega LM, Aguilar PM, Valdés HH, Martínez QR. Síndrome de Moebius. A propósito de un caso clínico. Rev Ciencias Médicas. 2011; 15(3): 1561-3194.
Vaccari CM, Tassano E, Torre M, Gimelli S, Divizia MT, Romanini MV et al. Assessment of copy number variations in 120 patients with Poland syndrome. BMC Med Genet. 2016; 17(1): 89.
Villafranca J, Castillo P, Garcés M, Villalón E, Grez E, Díaz A. Síndrome de Moebius. Rev Chilena de Cirugía. 2003; 55(1): 75- 80. Disponible en: http://www.imbiomed.com.mx/1/1/articulos. php?id_revista=163&idejemplar=4283
Cammarata-Scalisi F. Espectro clínico y etiológico del síndrome de Möbius. Arch Argent Pediatr. 2007; 105(5): 444-446.
Pereira JG, Schwarz K. The etiology of Möbius syndrome: a social problem? Int Arch Otorhinolaryngol. 2014; 18(3): 227-228.
Vieira VB, Tiller MM, Danda D, Carta A, Teixeira BC, Oliveira VL. Profile of ocular and systemic characteristics in Möbius sequence patients from Brazil and Italy. Arq Bras Oftalmol. 2012; 75(3): 202-206.
Pérez AA. Síndrome de Moebius. Proto Diag Ter Pediatr. 2010; 1: 80-84.
Guedes ZC. Möbius syndrome: misoprostol use and speech and language characteristics. Int Arch Otorhinolaryngol. 2014; 18(3): 239-243.
McClure P, Booy D, Katarincic J, Eberson C. Orthopedic manifestations of Mobius syndrome: case series and survey study. International Journal of Pediatrics. 2016; Article ID 9736723, p. 6.
Borbolla PA, Acevedo GP, Bosch CV, Ordaz FJ, Juárez EJ. Manifestaciones oculares y sistémicas del síndrome de Möebius. An Pediatr (Barc). 2014; 81(5): 297-302.
Srinivas MR, Vaishali DM, Vedaraju KS, Nagaraj BR. Mobious syndrome: MR findings. Indian J Radiol Imaging. 2016; 26(4): 502-505.
Gómez-Valencia L, Morales-Hernández A, Cornelio-García RM, Rivera-Angles MM. Estudio clínico y genético del síndrome de Moebius. Bol Med Hosp Infant Mex. 2008; 65(5): 353-357.
Tomas-Roca L, Tsaalbi-Shtylik A, Jansen JG, Singh MK, Epstein JA, Altunoglu U. De novo mutations in PLXND1 and REV3L cause Möbius síndrome. Nat Commun. 2015; 6: 7199. doi: 10.1038/ ncomms8199
Carrillo HC, Flores RC. Síndrome de Moebius. Rev Esp Med Quir. 2010; 15(4): 261-265.
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