Díaz SC, Navarro DD, Aladro HF, Fuentes DA, Acosta CA, Domínguez AE, González HO, Pérez PJ

Language: Spanish
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ABSTRACT

Introduction: atherosclerosis and osteoporosis are diseases with a high incidence. Several epidemiological studies have shown a relation among both processes.
Objective: to describe the possible relation among subclinical atherosclerosis and the decrease of bone´s mineral density, as well as the relations of these processes with reproductive variables in middle-aged women.
Methods: a cross-sectional descriptive study was conducted with 103 women who attended to the Climacteric and Osteoporosis Consultation in the National Institute of Endocrinology. Subclinical atherosclerosis was diagnosed through carotid doppler ultrasound, and bone´s mineral density by performing a dual x-ray absorptiometry in the lumbar spine. The chi square test of independence, the Pearson linear correlation coefficient, the t test for comparison of averages and Anova allowed the performance of the statistical analysis.
Results: subclinical atherosclerosis was diagnosed in 28 of the middle-aged women in the study (27 %), and 48 of them (46.6 %) had decreased bone´s mineral density (osteopenia or osteoporosis). 57.1 % of the patients with subclinical atherosclerosis had a decreased bone´s mineral density. 70.4 % of the patients with subclinical atherosclerosis were in the postmenopause stage; 66.7 % of those with osteopenia, and 75 % of those with osteoporosis were in the postmenopausal stage.
Conclusions: middle-aged women with subclinical atherosclerosis have more incidence of osteopenia or osteoporosis. In those with subclinical atherosclerosis and low bone´s mineral density, postmenopause is predominant. The type of menopause and the reproductive lifetime are not related to subclinical atherosclerosis and low bone´s mineral density. An inverse association among the postmenopausal time and bone´s mineral density is evidenced.