2001, Number 2
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Rev Endocrinol Nutr 2001; 9 (2)
Musculoskeletal alterations and obesity
Godínez GSA
Language: Spanish
References: 25
Page: 86-90
PDF size: 148.08 Kb.
ABSTRACT
The relationship between body weight or body fat and musculoskeletal complications has been documented in several studies. An increase in body weigth might be expected to add additional trauma to the weight carring joints, thereby accelerating the development of osteoarthritis, an age- related, noninflammatory disease of the diarthrodial joints characterized by degeneration and overgrowth of the cartilage and by overgrowth and sclerosis of the bone. The association between increased weigth and the risk for development of knee osteoarthritis is stronger in women than in men. There is no evidence that the development of osteoarthritis leads the subsequent onset of obesity. A decrease in bmi of 2 units or more during a 10-year period decrease the odds for developing knee osteoarthritis by more than 50 percent. weight gain was associated with a slight increase in risk. Obesity is also associated with an increased risk of gout. a significant correlation was seen between uric acid levels and weight, and was particulary marked in the age group 35 to 44, with somewhat lower correalation coefficients in the older age groups. Gout is also commoner in the obese. The musculoeskeletal pain osteoarthritis-related relieves with weight loss but returned when the weight was regained.
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