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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2018, Number 2

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An Med Asoc Med Hosp ABC 2018; 63 (2)

Neuroinfection by Listeria monocytogenes in an immunocompetent patient

Trujillo-Gutiérrez V, Campos-Jiménez KI, Mendoza-Aguilar R, Loza JSE

Language: Spanish
References: 17
Page: 125-128
PDF size: 171.45 Kb.


ABSTRACT

Meningitis is the inflammation of the meninges and the subarachnoid space that cover the cerebral cortex and parenchyma. Its etiology is commonly infectious and in case of being of bacterial origin, it is associated with a high morbi-mortality, and is considered an infectious emergency that requires immediate medical treatment. Listeria monocytogenes is the third cause of neuroinfection worldwide. The main risk factor is altered cellular immunity, for example, pregnant patients, neonates, chronic immunosuppression, HIV, over 60 years, cancer, among others. We present the case of a 47 year old previously healthy patient with meningitis due to Listeria monocytogenes. She was admitted to the emergency department for the presentation of headache, dizziness, perioral hypoaesthesia and lateropulsion. Laboratory studies were performed, initiating empirical antimicrobial treatment with ceftriaxone, ampicillin and acyclovir was started at meningeal doses. The cases of meningitis attributed to listeria in an immunocompetent young population, such as the patient presented here, are anecdotal. The diagnostic suspicion and the early start of the treatment are fundamental for a successful outcome.


REFERENCES

  1. Bennet J, Dolin R, Blaser M. Enfermedades infecciosas. Principios y práctica. 8a. edición. Elsevier Ltd; 2016, pp. 2514-2521.

  2. Arslan F, Meynet E, Sunbul M, Sipahi OR, Kurtaran B, Kaya S et al. The clinical features, diagnosis, treatment, and prognosis of neuroinvasive listeriosis: a multinational study. Eur J Clin Microbiol Infect Dis. 2015; 34 (6): 1213-1221.

  3. Van de Beek D, Brouwer M, Hasbun R, Koedel U, Whitney CG, Wijdicks E. Community-acquired bacterial meningitis. Nat Rev Dis Primers. 2016; 2: 16074.

  4. Southwick F. Infectious diseases a clinical short course. in: infectious diseases a clinical short course. 3rd ed. McGraw Hill; 2016, pp. 350-374.

  5. Mook P, O’Brien SJ, Gillespie IA. Concurrent conditions and human listeriosis, England, 1999-2009. Emerg Infect Dis. 2011; 17 (1): 38-43.

  6. Décard BF, Thöne J, Haghikia A, Börnke C, Anders A, Lukas C et al. Listeria rhombencephalitis mimicking a demyelinating event in an immunocompetent young patient. Mult Scler. 2017; 23 (1): 123-125.

  7. Mylonakis E, Hohmann EL, Calderwood SB. Central nervous system infection with Listeria monocytogenes. 33 years’ experience at a general hospital and review of 776 episodes from the literature. Medicine (Baltimore). 1998; 77 (5): 313-336.

  8. Disson O, Lecuit M. Targeting of the central nervous system by Listeria monocytogenes. Virulence. 2012; 3 (2): 213-221.

  9. Pagliano P, Arslan F, Ascione T. Epidemiology and treatment of the commonest form of listeriosis: Meningitis and bacteraemia. Infez Med. 2017; 25 (3): 210-216.

  10. Brouwer MC, Beek D Van De, Heckenberg SGB, Spanjaard L, de Gans J. Community-acquired Listeria monocytogenes meningitis in adults. Clin Infect Dis. 2006; 43 (10): 1233-1238.

  11. Chavada R, Keighley C, Quadri S, Asghari R, Hofmeyr A, Foo H. Uncommon manifestations of Listeria monocytogenes infection. BMC Infect Dis. 2014; 14: 641.

  12. Charlier C, Perrodeau É, Leclercq A, Cazenave B, Pilmis B, Henry B et al. Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study. Lancet Infect Dis. 2017; 17 (5): 510-519.

  13. Ooi ST, Lorber B. Gastroenteritis due to Listeria monocytogenes. Clin Infect Dis. 2005; 40 (9): 1327-1332.

  14. Pagliano P, Attanasio V, Rossi M, Carleo M, Carannante N, Ascione T. Listeria monocytogenes meningitis in the elderly: Distinctive characteristics of the clinical and laboratory presentation. J Infect. 2015; 71 (1): 134-136.

  15. Jamal WY, Al-Shomari S, Boland F, Rotimi VO. Listeria monocytogenes meningitis in an immunocompetent adult patient. Med Princ Pract. 2005; 14 (1): 55-57.

  16. Thigpen MC, Whitney CG, Messonnier NE, Zell ER, Lynfield R, Hadler JL et al. Bacterial Meningitis in the United States, 1998-2007. N Engl J Med. 2011; 364 (21): 2016-2025.

  17. Clauss HE, Lorber B. Central nervous system infection with Listeria monocytogenes. Curr Infect Dis Rep. 2008; 10 (4): 300-306.




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