2018, Number 1
<< Back Next >>
Anales de Radiología México 2018; 17 (1)
Interdisciplinary management of juvenile nasopharyngeal angiofibroma: presurgical embolization, surgical approach, and analysis of the literature
Peraza-McLiberty RA, Cortés-Benavides MC, Guerrero-Avendaño GML, Enríquez-García R, Graniel-Palafox LE
Language: Spanish
References: 32
Page: 20-29
PDF size: 796.88 Kb.
ABSTRACT
Introduction: Juvenile nasopharyngeal angiofibroma (JNA), also called nasopharyngeal angiofibroma,
is a benign, highly vascularized tumor, usually seen in male adolescents and boys. It
shows highly aggressive behavior due to local invasion and is associated with several symptoms.
JNA originates in the sphenopalatine foramen, causing nosebleed and nasal obstruction.
The surgical approach is complicated due to the large volume of associated bleeding. Presurgical
embolization largely reduces the volume of bleeding and facilitates extirpation of the tumor.
Objective: To present data on bleeding, surgical time, recovery time, and complications
associated with the procedure and describe the embolization technique.
Methods: Forty-nine patients were included, who were managed with embolization and conventional
surgical treatment. The subjects’ mean age was 15 years, and all subjects were male.
Results: Mean blood loss was 1,400 ml, less than that reported in the global literature for
surgery without prior embolization; recovery time was shorter and only one complication
was reported in the 49 patients treated.
Conclusions: Joint management of nasopharyngeal tumors with selective embolization
and subsequent surgical management offers better results in terms of bleeding and recovery
time and minimizes the risk of complications.
REFERENCES
Mena C, Abogado R, Klessen Z. Nuestra experiencia en los últimos 10 años y revisión de la Literatura. An ORL Mex. 2009;69:243-8.
Gaeta M. Nasoangiofibroma juvenil, frecuencia. Incidencia de acuerdo a grupo sanguíneo. An ORL Mex. 2005;50:17-21.
Wylie J, Slevin N, Johnson R. Intracranial juvenile nasopharyngeal angiofibroma. Clin Oncol. 1998;10:330-3.
Sánchez de Guzmán G. Experiencia en el manejo de nasoangiofibroma juvenil en el Instituto Nacional de Cancerología. Arch Otolaryngol Head Neck Surg. 1999;27:653-6.
Sociedade Brasileira de Otorrinolaringologia. Tratado de otorrinolaringología. Brasilia: Roca; 2003. p. 701-11.
Dillard D, Cohen C, Muller S, Del Gaudio J, Reichman O, Parrish B, et al. Immunolocalization of activated transforming growth factor 1 in juvenile nasopharyngeal angiofibrom. Arch Otolaryngol Head Neck Surg. 2000;126:723-5.
Mcafee W, Morris C, Andur R, Werning J, Mendenhall W. Definitive radiotherapy for juvenile nasopharyngeal angiofibroma. Am J Clin Oncol. 2006;29:168-70.
Pryor S, Moore E, Kasperbauer J. Endoscopic versus traditional approaches for excision of juvenile nasopharyngeal angiofibroma. Laryngoscope. 2005;115:1201-7.
Carvalho Júnior R, Mendonça C, D’Ávila J, Santos A, Jesus E, Sobral P. Abordagem endoscópica no tratamento do nasoangiofibroma: relato de caso. Braz J Otorhinolaryngol. 2005;71:4-19.
Bernal-Sprekelsen M, Alobid I, Guilemany JM. Angiofibroma juvenil. Acta Otorrinolaryngol. 2007;58:84-95.
Hervé S, Portier F, Chapot R. Fibroma nasofaríngeo. Encyclopedie Medico- Chirurgicale-Otorrinolaringologia. 2001;20:10.
Luiz ACR, Romualdo SLT, Fava AS. Angiofibroma nasofaríngeo: revisão de literatura. Braz J Otorhinolaryngol. 2003;69:394-403.
Nicolai P, Berlucchi M, Tomenzoli D. Endoscopic surgery for juvenile angiofibroma: when and how. Laryngoscope. 2003;113:775-82.
Maurice M, Milad M. Pathogenesis of juvenile nasopharyngeal fibroma (a new concept). Braz J Otorhinolaryngol. 1981;95:1121-6.
Andrade NA, Pinto JA, Nóbrega MO. Exclusively endoscopic surgery for juvenile nasopharyngeal angiofibroma. Arch Otolaryngol Head Neck Surg. 2007;137:492-6.
Gusso JL, Souza RP, Rapoport A. Nasoangiofibroma juvenil: concordância interobservadores no estadiamento por tomografia computadorizada. Radiol Bras. 2001;34:207-11.
Chandler JR. Nasopharyngeal angiofibromas: staging and management. Ann Otorhino Laryngol. 1984;93:322.
Sessions RB. Radiographic staging of juvenile angiofibroma. Head Neck Surg. 1981;3:279.
Radkowski D, McGill T, Healy GB, et al. Angiofibroma: changes in staging and treatment. Arch Otolaryngol Head Neck Surg. 1996;112:122-9.
Sivanandan E, Willard F. Benign and malignant tumors of the nasopharynx. En: Cummings CW, Haughey BH, Thomas JR, Harker LA, editores. Cummings Otolarynogology: head and neck surgery. Philadelphia: Mosby; 2005. p. 1669-84.
Andrews JC, Fisch U, Valavanis A, Aeppli U, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. Laryngoscope. 1989;99:429-37.
Sennes LU, Butugan O, Sánchez TG, Bento RF, Tsuji DH. Juvenile nasopharyngeal angiofibroma: the routes of invasion. Rhinology. 2001;41:235-40.
Onerci TM, Ogretmenoglu S, Yetiser S. Juvenile nasopharyngeal angiofibroma: a revised staging system. Rhinology. 2006;44:39-45.
Sennes LU, Butugan O, Sánchez TG, Bento RF, Tsuji DH. Juvenile nasopharyngeal angiofibroma: the routes of invasion. Rhinology. 2003;41:235-40.
Howard D, Lloyd G, Lund V. Recurrence and its avoidance in juvenile angiofibroma. Laryngoscope. 2001;111:1509.
Freihofer HPM. The timing of facial osteotomies in children and adolescents. Clin Plast Surg. 1982;9:445.
Yiotakis I, Eleftheriadou D, Davilis D, Giotakis E, Ferekidou E, Korres S, et al. Juvenile nasopharyngeal angiofibroma stages I and II: a comparative study of surgical approaches. Int J Pediatric Otorhino. 2008;72:793-800.
Lloyd G, Howard D, Phelps P, Cheesman A. Juvenile angiofibroma: the lessons of 20 years of modern imaging. J Laryngol Otol. 1999;113:127-34.
Lin KY. An experimental study on the effect of rigid fixation on the developing craniofacial skeleton. Plast Reconstruct Surg. 1991;87:229.
Martins MBB, De Lima FVF, Mendonça CA, De Jesus EPF, Santos ACG, Barreto VMP, et al. Nasopharyngeal angiofibroma: our experience and literature review. Int Arch Otorhinolaryngol. 2013;17:14-9.
Katsiotis P, Tzortzis G, Karaminis C. Transcatheter arterial embolization in nasopharyngeal angiofibroma. Acta Radiol Diagn. 1979;20:433-8.
Gay I, Elidan J, Gordon R. Oronasal fistula, a possible complication of preoperative embolization in the management of juvenile nasopharyngeal angiofibroma. J Laryngol Otol. 1983;97:651-6.