2017, Number 5
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AMC 2017; 21 (5)
Myxoid liposarcoma of the thigh: a case report
Álvarez LA, Hernández VA, García LYC, del Risco TCA, Rojo QN
Language: Spanish
References: 10
Page: 639-645
PDF size: 587.54 Kb.
ABSTRACT
Background: malignant soft tissue tumors are not common, but among them liposarcoma has the higher incidence.
Objective: to show a patient with a myxoid liposarcoma of the thigh.
Case report: a 49-year-old white man, with record number 207009. The patient was taken to the Outpatient Orthopedic Department because of a soft tissue mass found in the right thigh for about six years, which in the last six months grew quickly. There was no pain and the patient refused medical assistance because of fear. On palpation a big soft tissue mass was detected with irregular margins, mix consistency, location under the fascia, deep-seated tumor although not fixed to the bone, and 30 centimeters long, 20 centimeters width and 15 centimeters deep found on the right thigh. Imaging exams like ultrasound, computed axial tomography, magnetic resonance imaging and arteriography were performed. The patient underwent surgery and a wide resection was carried out by a team of orthopedics, angiologists, general surgeons and anesthesiologists. Tumor resection was done by a safe margin.
Conclusions: myxoid liposarcoma is the most common soft tumor as well as its location at the appendicular skeleton, like the thigh.
REFERENCES
1.Spiguel A. Soft tissue sarcomas. En: Peabody TD, Attar S, editores. Orthopaedic Oncology. New York: Springer; 2014. p. 203-5.
2.Vigorita VJ. Orthopaedic Pathology. 3 rd ed. Philadelphia: Wolters Kluwer; 2016.
3.Manji GA, Schwartz GK. Managing liposarcomas: cutting through the fat. J Oncol Pract. 2016 Mar;12(3):221-7.
4.Bekers EM, Song W, Suurmeijer AJ, Bonenkamp JJ, van der Geest IC, Braam PM, et al. Myxoid liposarcoma of the foot: a study of 8 cases. Ann Diagn Pathol. 2016 Dec;25:37-41.
5.Crago AM, Dickson MA. Liposarcoma: multimodality management and future targeted therapies. Surg Oncol Clin N Am. 2016 Oct;25(4):761-73.
6.Reshadi H, Rouhani A, Mohajerzadeh S, Moosa M, Elmi A. Prevalence of malignant soft tissue tumors in extremities: an epidemiological study in Syria. Arch Bone Jt Surg. 2014 Jun;2(2):106-10.
7.Child JR, Young CR, Amini B. Liposarcoma of the thigh with mixed calcification and ossification. Radiol Case Rep. 2016 Jul;11(3):217-21.
8.Löwenthal D, Zeile M, Niederhagen M, Fehlberg S, Schnapauff D, Pink D, et al. Differentiation of myxoid liposarcoma by magnetic resonance imaging: a histopathologic correlation. Acta Radiol. 2014 Oct;55(8):952-60.
9.Wortman JR, Tirumani SH, Jagannathan JP, Tirumani H, Shinagare AB, Hornick JL, et al. Primary extremity liposarcoma: MRI features, histopathology, and clinical outcomes. J Comput Assist Tomogr. 2016 Sep-Oct;40(5):791-8.
10.Iura K, Kohashi K, Hotokebuchi Y, Ishii T, Maekawa A, Yamada Y, et al. Cancer-test is antigens PRAME and NY-ESO-1 correlate with tumour grade and por prognosis in myxoid liposarcoma. J Pathol Clin Res. 2015 Mar;1(3):144-59.