2018, Number 1
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Rev Mex Urol 2018; 78 (1)
The effect of percutaneous tibial nerve stimulation on patients with monosymptomatic enuresis: An initial experience in Mexico
Pérez-Martínez C, Palacios-Galicia JL, Vargas-Díaz IB, Cruz-Gómez Y
Language: Spanish
References: 39
Page: 19-27
PDF size: 291.74 Kb.
ABSTRACT
Objective: The aim of our study was to evaluate the effect of six
sessions of posterior tibial nerve stimulation on patients with treatmentrefractory
monosymptomatic enuresis and to describe the risk factors
of the technique.
Materials and Methods: A prospective, randomized, controlled
clinical trial was conducted on patients between 6 and 15 years of age
that presented with monosymptomatic enuresis of six-month progression
that did not respond to first-line or second-line treatments. The
patients were randomly assigned to one of two groups: 1) active group
(with electrical stimulation) and 2) placebo group (without electrical
stimulation). Six posterior tibial nerve stimulation sessions were applied
to the active group patients and six sham sessions to the placebo group
patients. The study variables were age, sex, socioeconomic status,
enuresis progression, bladder diary (before and after treatment), and
uroflowmetry. Data normality was determined through the Shapiro-
Wilk test and the Student’s t test was employed in the comparisons of
sex and treatment type between the groups.
Results: Eight patients were recruited for the study, 4 boys and 4
girls, and their mean age was 10.6 ± 1.6 years. There was no statistically
significant difference in age or sex between the two groups.
Patient improvement (“dry” nights) was 80 ± 7.5% in the active group
vs 3.7 ± 1.2% in the placebo group (p‹0.001). There were very few
adverse effects.
Conclusions: The effect of six sessions of neuromodulation through
posterior tibial nerve stimulation as treatment for refractory monosymptomatic
enuresis was effective, low-cost, easily reproducible, and had
almost no adverse effects.
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