2018, Number 1
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Acta Med 2018; 16 (1)
Liver B-cell lymphoma
Castillo-García J, Montes de Oca-Orellana R, León-Merino G, Cartagena-Sotres E, Zubieta-O’Farrill G, Carballal-Lozada MF
Language: Spanish
References: 11
Page: 54-57
PDF size: 280.42 Kb.
ABSTRACT
The primary hepatic lymphoma is an unusual type of non-Hodgkin lymphoma that clinically manifests with consumption symptoms, hepatomegaly and jaundice with obstructive pattern, there is no presence of lymphadenomegaly, or extra-hepatic invasion in early stages. Its prevalence is approximately 4% of non-Hodgkin extra nodal lymphomas and 0.016% of all lymphomas. We present a 68-year-old woman who presented with colic, epigastric, abdominal pain, irradiated to the right upper quadrant, associated with nausea, vomit in multiple occasions, and 39
oC fever. After a full diagnostic workup, multiple hepatic lesions were identified and a left hepatectomy is performed. Pathology reported a type B giant cells diffuse lymphoma. non-Hodgkin lymphoma has a liver presentation in up to 40% of all cases, and generally as a late manifestation of the disease. Nonetheless, the primary hepatic lymphoma (PHL), without involvement of other organs is infrequent. Almost 67% of patients that present PHL are adult, with non-specific symptoms in 37%, such as abdominal pain, nausea, fever, weight loss, among others, like our patient who initiated with abdominal pain.
REFERENCES
Ma YJ, Chen EQ, Chen XB, Wang J, Tang H. Primary hepatic diffuse large B cell lymphoma: A case report: Primary hepatic diffuse large B cell lymphoma. Hepat Mon. 2011; 11 (3): 203-205.
Leung VK, Lin SY, Loke TK, Chau TN, Leung CY, Fung TP et al. Primary hepatic peripheral T-cell lymphoma in a patient with chronic hepatitis B infection. Hong Kong Med J. 2009; 15 (4): 288-290.
Cerban R, Gheorghe L, Becheanu G, Serban V, Gheorghe C. Primary focal T-cell lymphoma of the liver: a case report and review of the literature. J Gastrointestin Liver Dis. 2012; 21 (2): 213-216.
Emile JF, Azoulay D, Gornet JM, Lopes G, Delvart V, Samuel D et al. Primary non-Hodgkin’s lymphomas of the liver with nodular and diffuse infiltration patterns have different prognoses. Ann Oncol. 2001; 12 (7): 1005-1010.
Stancu M, Jones D, Vega F, Medeiros LJ. Peripheral T-cell lymphoma arising in the liver. Am J Clin Pathol. 2002; 118 (4): 574-581.
Zentar A, Tarchouli M, Elkaoui H, Belhamidi MS, Ratbi MB, Bouchentouf SM et al. Primary hepatic lymphoma. J Gastrointest Cancer. 2014; 45 (3): 380-382.
Kim HS, Ko YH, Ree HJ. A case report of primary T-cell lymphoma of the liver. J Korean Med Sci. 2000; 15 (2): 240-242.
Lei KI. Primary non-Hodgkin’s lymphoma of the liver. Leuk Lymphoma. 1998; 29 (3-4): 293-299.
Weinreb JC, Brateman L, Maravilla KR. Magnetic resonance imaging of hepatic lymphoma. AJR Am J Roentgenol. 1984; 143 (6): 1211-1214.
Ben-Haim S, Bar-Shalom R, Israel O, Gaitini D, Hahn N, Epelbaum R et al. Liver Involvement in Lymphoma: role of gallium-67 scintigraphy. J NucI Med. 1995; 36: 900-904.
Castroagudín JF, Molina E, Abdulkader I, Forteza J, Delgado MB, Domínguez-Muñoz JE. Sonographic features of liver involvement by lymphoma. J Ultrasound Med. 2007; 26 (6): 791-796.