Ceballos-López AA

Language: Spanish
References: 36
Page: 17-23
PDF size: 269.14 Kb.

ABSTRACT

Although the exact incidence and prevalence of chronic lymphocytic leukemia in Mexico is unknown, in epidemiological reports it is considered the less frequent leukemia between acute and chronic leukemias, unlike in Europe and the United States, where it is the most frequent. There are well known prognostic and predictive factors for the disease, but in recent years there is evidence to support that obtaining a minimum negative residual disease, regardless of the initial prognostic factors or treatment, is the most important predictive factor for progression free and global survival. This article reviews the methods to evaluate the minimum residual disease, the site to obtain the sample for its analysis and the minimum negative residual disease rates obtained with different therapeutic schemes trying to apply them in the Mexican reality.

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