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ISSN 1995-9494 (Electronic)
Revista del Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

2018, Number 1

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Acta Med Cent 2018; 12 (1)

Valor diagnóstico de la citología del lavado y el cepillado bronquial en el cáncer de pulmón

Vargas GS, Ruiz JL

Language: Spanish
References: 14
Page: 1-9
PDF size: 196.87 Kb.


ABSTRACT

Introduction: lung cancer is the most frequent and one of the deadliest in the world. Objective: to evaluate the diagnostic value of bronchial washing and brushing in lung cancer. Method: an observational, descriptive, cross-sectional study was conducted in “Arnaldo Milián Castro” Hospital of the Province of Villa Clara in the period between January 2009 and December 2010. The sample was constituted by 185 patients who were performed bronchoscopy with bronchial biopsy and washing, brushing or both. Results: 76,4% of useful samples were obtained with the bronchial brushing, while with the washing was only 38,8%. The lung cancer variant that was most frequently diagnosed by cytology and biopsy was squamous carcinoma. With bronchial brushing, there were 25,4% of diagnostic errors and 28,8% with washing. The sensitivity was low in bronchial lavage (40%) and 67,5% in brushing, while the specificity was high for both cytological studies (97,2% and 89,5% respectively). The efficacy was 71,2% for washing and 74,6% for bronchial brushing. In the COR curves the washing and brushing showed areas under the curve of 0,69 (poor predictive capacity) and 0,79 (acceptable predictive capacity), respectively. Conclusions: bronchial brushing showed to be a superior method to washing in the diagnosis of lung cancer due to the greater percentage of useful samples, to the mayor coincidence with bronchial biopsy, to a superior overall efficacy and greater predictive capacity.


REFERENCES

  1. Hussain A. The Lung. In: Kumar V, Abbas A, Aster J. Robbins Basic Pathology [Internet]. 9th ed. Chicago: Elsevier; 2013 [citado 16 Feb 2017]. p. 459-515. Disponible en: https://www.elsevier.com/books/robbins-basic-pathology/kumar/978-1-4377-1781-5

  2. Ahmad M, Afzal S, Saeed W, Mubarik A, Saleem N, Khan S, et al. Efficacy of bronchial wash cytology and its correlation with biopsy in lung tumours. J Pak Med Assoc [Internet]. 2004 Jan [citado 16 Feb 2017];54(1):13-6. Disponible en: http://www.jpma.org.pk/full_article_text.php?article_id=320

  3. Ministerio de Salud Pública, Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud 2016. 45 ed. La Habana, Cuba: Producciones Gráficas Cedisap; 2017. 206 p.

  4. Amorín Kajatt E. Cáncer de pulmón, una revisión sobre el conocimiento actual, métodos diagnósticos y perspectivas terapéuticas. Rev Perú Med Exp Salud Pública [Internet]. 2013 Ene [citado 29 Mar 2017];30(1): 85-92. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1726-46342013000100017&lng=es

  5. Ofiara LM, Navasa kulpong A, Ezer N, González AV. The importance of a satisfactory biopsy for the diagnosis of lung cancer in the era of personalized treatment. Curr Oncol. 2012 Jun;19(Suppl 1): S16–S23 doi: 10.3747/co.19.1062 PMCID: PMC3377750

  6. Rawat J, Sindhwani G, Saini S, Kishore S. Usefulness and cost effectiveness of bronchial washing in diagnosing endobronchial malignancies. Lung India [Internet]. 2007 [citado 29 Mar 2017];24(4):139-141. Disponible en: http://www.lungindia.com/text.asp?2007/24/4/139/44378

  7. Galen R, Gambino SR. Beyond normality: the predictive value and efficiency of medical diagnosis. A Wiley biomedical publication [Internet]. New York: Churchill Livingstone; 1976 [citado 29 Mar 2017]. 254p. Disponible en: https://www.amazon.com/Beyond-Normality-Predictive-Efficiency-publication/dp/0471290475

  8. Parkin M, Tyczynski J, Boffetta P. Tumours of the lung. In: Travis W, Brambilla E, Muller K (edit.). WHO Classification of tumours. Tumours of the lung, pleura, thymus and heart. Lion: IARC Press; 2004. p. 10-122.

  9. Mufti S, Mokhtar G. Diagnostic value of bronchial wash, bronchial brushing, fine needle aspiration cytology versus combined bronchial wash and bronchial brushing in the diagnosis of primary lung carcinomas at a tertiary care hospital. Biomed Res [Internet]. 2015 [citado 29 Mar 2017];26(4):777-84. Disponible en: http://www.biomedres.info/biomedical-research/diagnostic-value-of-bronchial-wash-bronchial-brushing-fine-needle-aspiration-cytology-versus-combined-bronchial-wash-and-bronchial.html

  10. 10.DeMay R. Respiratory Cytology. In: The art and science of cytopathology. Chicago: ASCP Press; 1996. p. 55-72.

  11. 11.Vivekanand N, Smita A, Durga K. Efficacy of bronchial wash and brush cytology in the diagnosis of lung cancers. Sch J App Med Sci. 2014;2(2D):816-20.

  12. 12.Rosai J. Respiratory tract: nasal cavity, paranasal sinuses, and nasopharynx, larynx and trachea, lung and pleura. In: Rosai J, Ackerman L. Surgical Pathology. 10th ed. España: Elsevier; 2011. p. 366-84.

  13. 13.Bodh A, Kaushal V, Kashyap S, Gulati A. Cytohistological correlation in diagnosis of lung tumors by using fiberoptic bronchoscopy: Study of 200 cases. Indian J Pathol Microbiol [Internet]. 2013 Apr-Jun [citado 13 Jul 2017];56(2):84-8. Disponible en: http://www.ijpmonline.org/text.asp?2013/56/2/84/118661

  14. 14.Gaur DS, Thapliyal N, Kishore S, Pathak V. Efficacy of broncho-alveolar lavage and bronchial brush cytology in diagnosing lung cancers. J Cytology [Internet]. 2007 [citado 13 Jul 2017];24(2):73-77. Disponible en: http://www.jcytol.org/article.asp?issn=0970-9371;year=2007;volume=24;issue=2;spage=73;epage=77;aulast=Gaur




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