2004, Number 3
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Rev Fac Med UNAM 2004; 47 (3)
Benign peritoneal mesothelioma
Padilla RAL, Hernández GM, Alcántara VA
Language: Spanish
References: 18
Page: 125-128
PDF size: 59.42 Kb.
ABSTRACT
Benign Multicystic Mesothelioma (BMM) is a very rare lesion that arises mainly from mesothelial cells of the pelvic peritoneum and may involve the whole abdominal cavity.
The case of a 40-year old woman with pelvic pain and abdominal distension is presented. Abdomino-pelvic ultrasound and computerized tomography showed multiple cystic lesions. A laparotomy a multicystic lesion was found that involved the abdomino-pelvic cavity. The tumor was partially removed, sized 23 x 20 x 8 cm, and showed a smooth-surface cysts with serous to mucinous intracystic fluid, intermingled with adipose tissue. Histologically the cysts were lined by a single layer of flat to cuboidal mesothelial cells, some of them with a hobnail appearance, and separated by thin fibrous septa. Immunohistochemically the mesothelial cells were positive to HBME-1 and negative to vascular markers. This is important to differentiate it from cystic lymphangiomas.
Clinical presentation, degree of extension and the high ability of recurrence support the neoplastic character of this tumor. Although controversy about the neoplastic vs hyperplastic nature of this lesion still exist, we consider that BMM is a true neoplasm of intermediate malignancy between adenomatoid tumor and malignant mesothelioma.
REFERENCES
Caropreso PR. Mesenteric cysts: a review. Arch Surg 1974; 108: 242-246.
Suzuki Y, Kannerstein M. Ultrastructure of human malignant diffuse mesothelioma. Am J Pathol 1976; 85: 241-262.
Bolen JW, Thorning D. Mesotheliomas: a light and electron microscopical study concerning histogenetic relationships between the epithelial and the mesenchymal variants. Am J Surg Pathol 1980; 4: 451-464.
Battiffora H, McCaughey WTE. Atlas of tumor pathology: Tumors of the serosal membranes. Third series. Washington, D.C. Armed Forces Institute of Pathology; 1995.
Mennemeyer R, Smith M. Multicystic peritoneal mesothelioma: a report with electron microscopy of a case mimicking intra-abdominal cystic hygroma (lymphangioma). Cancer 1979; 44: 692-698.
Ross MI, Welch WR, Scully RE. Multilocular peritoneal inclusion cysts (so-called cystic mesotheliomas). Cancer 1989; 64: 1336-1346.
Katsube Y, Mukai K, Silverberg SG. Cystic mesothelioma of the peritoneum: a report of five cases and review of the literature. Cancer 1982; 50: 1615-1622.
Moore J, Crum CP, Chandler J, Feldman PS. Benign cystic mesothelioma. Cancer 1980; 45: 2395-2399.
Ball NJ, Urbanski SI, Green FHY, Kierser T. Pleural multicystic mesothelial proliferation: the so-called multicystic mesothelioma. Am J Surg Pathol 1990; 14: 375-378.
Weiss SW, Tavassoli FA. Multicystic mesothelioma: an analysis of pathologic findings and biologic behavior in 37 cases. Am J Surg Pathol 1988; 12: 737-746.
Nideri NS, Lowry DS, Wallace RJ. Cystic mesothelioma of the pelvic peritoneum: two cases report. Br J Obstet Gynaecol 1984; 91: 201-204.
Schneider V, Partridge JR, Gutierrez F, Hurt WG, Mazels MS, Demay RM. Benign cystic mesothelioma involving the female genital tract: report of four cases. Am J Obstet Gynaecol 1983; 145: 355-359.
Schneider JA, Zelnick EJ. Benign cystic peritoneal mesothelioma. J Clin Ultrasound 1985; 12: 190-192.
Miles JM, Hart WR, McMahen JT. Cystic mesothelioma of the peritoneum: report of a case with multiple recurrences and review of the literature. Cleve Clin Q 1986; 53: 109-114.
Rosai J, Dehner LP. Nodular mesothelial hyperplasia in hernia sacs: a benign reactive condition simulating a neoplastic process. Cancer 1975; 35: 165-175.
Quigley JC, Hart WR. Adenomatoid tumors of the uterus. Am J Clin Pathol 1981; 76: 627-6635.
Taxy JB, Battigora H, Oyasu R. Adenomatoid tumors: a light microscopic, histochemical, and ultrastructural study. Cancer 1974; 34: 306-316.
Galifer RB, Pous JG, Juskiewenski S, Pasquie M, Gaubert J. Intraabdominal cystic lymphangiomas in childhood. Prog Pediatr Surg 1972; 11: 173-238.