Hernández CM, Iglesias CTC, Abascal GH

Language: Spanish
References: 0
Page: 471-479
PDF size: 332.32 Kb.

ABSTRACT

Introduction: early jaundice due to isoimmunization ABO is cause of frequent hospitalization in Neonatology service. Objective: to characterize newborns with ABO isoimmunization in Pinar del Río province. Method: an observational, descriptive and cross-sectional study was carried out in the Neonatology service at Abel Santamaría Cuadrado General Teaching Hospital in Pinar del Río during 2015. Target group: 98 newborns older than or equal to 34 weeks of gestational age admitted to Neonatal Intensive Care Unit diagnosed as maternal-fetal isoimmunization. Sample: infants with early jaundice by ABO isoimmunization (n = 67). Infants with early jaundice and associated morbidity were excluded, as well as those with concomitant of the two conflicts (RH and ABO). Results: the incidence of ABO isoimmunization with respect to total births was 1.08% and related to maternal fetal blood conflicts was 56.1%. In 67.2% gestational age was greater than or equal to 37 weeks, with 74.5% being in primigravidae, more frequent in males (52.7%). Jaundice was the main form of presentation (50.9%), and appeared between 12 and 24 hours of life in 65.4%. The predominant incompatibility was O-A (52.7%), 98.1% presented Coombs direct negative test, severe hyperbilirubinemia developed 77.7%. Intacglobin was used in 30.0% and exchange transfusion in 7.2%. Conclusion: ABO isoimmunization is a frequent cause of severe hyperbilirubinemiabetween the second and seventh days of life, indirect bilirubindetermined between 24 and 36 hours of life allowing the identification of newborns with the possibility of developing severe hyperbilirubinemia of the newborn.