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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2017, Number 4

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An Med Asoc Med Hosp ABC 2017; 62 (4)

Cutaneous myofibroma of the glans penis

Sánchez RCB, Cano GF, Díaz FLA, Sánchez SF

Language: Spanish
References: 11
Page: 279-282
PDF size: 263.47 Kb.


ABSTRACT

Penile tumors are rare in children; penile myofibroma is even rarer. We describe the case of a two-year-old Caucasian male with two asymptomatic nodules detected in the ventral penile region. An excisional biopsy was performed of both fibrous lesions. The histopathology report indicated deep dermis with benign mesenchymal neoplasm and nodular pattern, with ill-defined borders, unencapsulated, separated from the epidermis by a segment of unaltered reticular dermis; the arrays of elongated myofibroblasts were positive for vimentin and actin. After 24 months of follow-up, the patient has remained asymptomatic, with no evidence of new lesions. Solitary myofibromas are a rare benign neoplasm which can only be diagnosed by histopathology. Excision of the lesion is often curative. It must be continually monitored to rule out the risk of recurrence. Myofibroma should be included in the differential diagnosis of penile tumors. To our knowledge, this is the fifth case of penile myofibroma, but the first one with the presence of two myofibromas.


REFERENCES

  1. Gopal M, Chahal G, Al-Rifai Z, Eradi B, Ninan G, Nour S. Infantile myofibromatosis. Pediatr Surg Int. 2008; 24 (3): 287-291.

  2. Fasola-Maccari ML, Manfrin L, Galluzo ML, Scrigni AV. Miofibromatosis infantil: reporte de un caso y revisión de la literatura. Bol Med Hosp Infant Mex. 2011; 68 (4): 296-301.

  3. Stout AP, Murray MR. Hemangiopericytoma: a vascular tumor featuring Zimmermann’s pericytes. Ann Surg. 1942; 116 (1): 26-33.

  4. Chung EB, Enzinger FM. Infantile myofibromatosis. Cancer. 1981; 48 (8): 1807-1818.

  5. Rao MV, Polcari I, Barkan GA, Hatch DA. Penile myofibroma occurring in a dorsal hood prepuce. Urology. 2011; 77 (3): 726-727.

  6. Val-Bernal JF, Garijo MF. Solitary cutaneous myofibroma of the glans penis. Am J Dermatopathol. 1996; 18 (3): 317-321.

  7. Fletcher CDM, Unni KK, Mertens F, eds. World Health Organization Classification of Tumors. Pathology and genetics of tumours of soft tissue and bone. Lyon, France: IARC Press; 2002. pp. 59-61. Disponible en: http://www.iarc.fr/en/publications/pdfs-online/ pat-gen/bb5/BB5.pdf

  8. Roggli VL, Kim HS, Hawkins E. Congenital generalized fibromatosis with visceral involvement. A case report. Cancer. 1980; 45 (5): 954-960.

  9. Brill PW, Yandow DR, Langer LO, Breed AL, Laxova R, Gilbert EF. Congenital generalized fibromatosis. Case report and literature review. Pediatr Radiol. 1982; 12 (6): 269-278.

  10. Wiswell TE, Davis J, Cunningham BE, Solenberger R, Thomas PJ. Infantile myofibromatosis: the most common fibrous tumor of infancy. J Pediatr Surg. 1988; 23 (4): 315-318.

  11. Eisner BH, McAleer SJ, Gargollo PC, Perez-Atayde A, Diamond DA, Elder JS. Pediatric penile tumors of mesenchymal origin. Urology. 2006; 68 (6): 1327-1330




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