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2017, Number 4

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Rev Hosp Jua Mex 2017; 84 (4)

Oral hypoglycemic agents for the treatment of diabetes mellitus type 2: use and regulation in Mexico

Rodríguez-Rivera NS, Cuautle-Rodríguez P, Molina-Guarneros JA

Language: Spanish
References: 64
Page: 203-211
PDF size: 232.82 Kb.


ABSTRACT

According to its action mechanism, there are five groups of oral hypoglycemic agents for the treatment of diabetes mellitus type 2: insulin secretagogues (sulphonylureas and glinides), insulin sensitizers (biguanides and thiazolidinediones), α-glucosidase inhibitors, GLP-1 agonists, and DPP-4 inhibitors. Mexican regulation (NOM-015-SSA2010) and clinical guides contemplate the use of these drugs based on reported scientific evidence. The real basic drug-use chart does not completely correspond to this current regulation. Some drugs already retired from the market in other countries due to their side effects are still in use in our country and considered in the basic drug-use chart. There are few data on the cost-benefit of the currently recommended drugs against diabetes mellitus type 2. There is not enough information to justify the addition or exclusion of drugs to the basic medical scheme. Recent data indicate that there is a poor availability of drugs to treat chronic diseases in the public health system. This causes an expense increase for patients as well as a decrease in the control of the disease. It is necessary to reconsider and unify both drug use and supply policies, considering the data present in the available literature and the conditions and needs of our population.


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