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ISSN 1025-0255 (Electronic)

2017, Number 3

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AMC 2017; 21 (3)

Malignant pleomorphic storiform fibrous histiocytoma of the left arm

Hernández GEH, Mosquera BG, Rondón ME

Language: Spanish
References: 11
Page: 370-377
PDF size: 519.48 Kb.


ABSTRACT

Background: malignant fibrous histiocytoma is the most frequent soft tissue sarcoma in adulthood. It is seen in extremities in about 70-75 % and lower limbs are the most affected ones with 60 %.
Objective: to present a case of malignant storiform pleomorphic histiocitoma of the left arm who underwent surgical treatment at universitary hospital Manuel Ascunce Domenech of Camagüey in 2016.
Clinical case: a 60 year old male patient with a round increasing volume in posterolateral proximal left arm with collateral circulation. It was palpated a 20 cm diameter smooth, firm, fix to deep planes and painful mass with negative auscultation. Simple left humerus radiography informed a homogeneous radiopacity in surrounding soft tissues, no periosteal reaction or bone damage. Ecography of soft tissues: hypoecoic image of 200 x 170 mm between triceps and deltoid muscles reaction, with well defined pseudocapsule and no bone affection. An aspiration biopsy was done which inform a malignant mesenchimal neoplasia as a possible malignant histiocytoma. Surgical treatment was carried out to remove the tumor with oncologic margins. Final biopsy after immunohystochemical staining revealed a malignant fibrous pleomorphic storiform histiocytoma. The patient was sent to oncologic treatment with radiotherapy and a local recurrence was diagnosed, that is why a four quarter amputation was achieved.
Conclusions: malignant fibrous histiocytoma is the most frequent soft tissue sarcoma in adulthood. There are different histological varieties, that is why immunohystochemical staining is a key tool for accurate diagnosis. Surgery and radiotherapy are the best therapeutic combination. Age, tumor depth, histological variety, location, absence of metastasis and size are the most important prognosis factors.


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