Arellano AG, Salas MI, Rodríguez GN, Núñez MES, Domínguez CLG

Language: Spanish
References: 14
Page: 296-300
PDF size: 184.14 Kb.

ABSTRACT

Background: Pulmonary fibrosis is a chronic condition with high morbidity and mortality in 25% of patients with interstitial lung disease, Myasthenia Gravis is an autoimmune disease with antibodies to acetylcholine receptors at the neuromuscular junction, and Hashimoto’s thyroiditis is an autoimmune disease with anti-thyroid antibodies. His association is extraordinary, with only one literature report. Clinical cases: Female of 69 years with 11 years evolution characterized by cough, dyspnea gradually evolving, plus diplopia, and clinical data hypothyroidism; with positives Anti thyroglobulin antibody, thyroid peroxidase, anti-acetylcholine receptor antibodies and anti-nuclear antibodies. Conclusions: Autoimmune overlap between MG and other autoimmune disorders reflects common pathogenic mechanisms. Myasthenia gravis and autoimmune thyroid disease association is rare; the association of pulmonary fibrosis and autoimmune thyroid disease is very rare, and the association of myasthenia gravis, Hashimoto thyroiditis and pulmonary fibrosis is extraordinary.

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