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2016, Number 4

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Rev Cubana Plant Med 2016; 21 (4)

Evaluation of the biological activity of extracts from Commiphora leptophloeos (Mart.) J. B. Gillet

Cavalcanti CEL, Silva SJ, de Castro FD, Dantas MAC, Silva H, Pereira CT

Language: Portugués
References: 39
Page: 1-10
PDF size: 117.03 Kb.


ABSTRACT

Introduction: Commiphora leptophloeos (Mart.) J. B. Gillet (Burseraceae) is a species used in traditional medicine in the semiarid region of Brazil to treat a variety of conditions, particularly infectious diseases.
Objective: Evaluate the biological activities of C. leptophloeos extracts obtained by various extraction techniques.
Methods: The stem extracts were obtained by maceration, percolation, ultrasound and turbolise, and subjected to phytochemical analysis, microbial sensitivity testing by microdilution and acute toxicity testing against Artemia salina.
Results: The highest polyphenol and flavonoid concentrations were found in the extracts obtained by turbolise. C. leptophloeos extracts were effective against S. aureus and showed moderate toxicity.
Conclusions: The plant contains secondary metabolites with important pharmacological activities and antimicrobial activity against S. aureus. Further studies are required to evaluate the viability of this plant for the development of new drugs.


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