Cavalcanti CEL, Silva SJ, de Castro FD, Dantas MAC, Silva H, Pereira CT

Idioma: Portugués
Referencias bibliográficas: 39
Paginas: 1-10
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RESUMEN

Introducción: Commiphora leptophloeos (Mart.) J. B. Gillet (Burseraceae) es una especie usada en la medicina tradicional de la región semiárida de Brasil contra diversas enfermedades, con énfasis en las enfermedades infecciosas.
Objetivo: evaluar las actividades biológicas de los extractos de C. leptophloeos obtenidos por diferentes técnicas de extracción.
Métodos: los extractos de la corteza se obtuvieron por maceración, percolación, ultrasonido y turbólise. Fueron sometidos a ensayos fitoquímicos, pruebas de sensibilidad microbiana por microdilución y toxicidad aguda sobre Artemia salina.
Resultados: las concentraciones más altas de polifenoles y flavonoides fueron encontrados en los extractos por turbólise. Los extractos de C. leptophloeos fueron eficaces contra S. aureus y mostraron toxicidad moderada.
Conclusiones: la planta posee metabolitos secundarios con actividades farmacológicas importantes y actividad antimicrobiana frente S. aureus, otros estudios son necesarios para evaluar la viabilidad de esta planta para el desarrollo de nuevos fármacos.

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