2017, Number 3
<< Back Next >>
Residente 2017; 12 (3)
Environmental risk factors associated with acute lymphoblastic leukemia in children. Case control study
Agramón-Velázquez R, Haro-Acosta ME, De León-Figueroa R, Barreras-Serrano A
Language: Spanish
References: 14
Page: 84-88
PDF size: 294.73 Kb.
ABSTRACT
Introduction: Acute lymphoblastic leukemia (ALL) is the most commonly diagnosed neoplasm in patients younger than 15 years, although some factors such as tobacco and alcohol are related; there is still little information about the environment.
Objective: To determine the environmental risk factors associated with ALL in children.
Material and methods: Case-control study, analytical and cross-sectional in the period January 2016 to May 2017. The sample size was non-probabilistic. Within the risk factors associated for assessment, were: exposure to pesticides, electromagnetic fields, smoking, and alcohol during pregnancy, history of cancer and familial haematological disease. It was paired with two controls; data were analyzed with statistical methods odds ratio and confidence interval with SAS 9.4 statistical program.
Results: There were 17 cases and 34 controls, male predominated, mean age was 7.29; The environmental risk factor with statistical significance was exposure to electromagnetic fields with an OR 4.06 (CI:1.05-15.3) p ≤ 0.05.
Conclusion: The environmental risk factor for ALL was exposure to electromagnetic fields.
REFERENCES
Rendón-Macías ME, Reyes-Zepeda NC, Villasís-Keeve MA, Serrano-Meneses J, Escamilla-Núñez A. Tendencia mundial de la supervivencia en pacientes pediátricos con leucemia linfoblástica aguda. Bol Med Hosp Infant Mex. 2012; 69 (3): 153-163.
Ortega-Sánchez MA, Osnaya-Ortega ML, Rosas-Barrientos JV. Leucemia linfoblástica aguda. Med Int Mex. 2007; 23 (1): 26.
Estrada-Padilla SA, Corona-Rivera JR, Sánchez-Zubieta F, Bobadilla-Morales L, Corona-Rivera A. Variantes fenotípicas en pacientes con leucemia linfoblástica del occidente de México. An Pediatr (Barc). 2015; 82 (2): 75-82.
Jaime-Pérez JC Gómez-Almaguer D. Hematología La sangre y sus enfermedades. 2da ed. Mc Graw Hill editorial: 2009. Capítulo 16, Leucemia Linfoblástica Aguda; 71-76.
Seiter K, Besa CE. Acute Lymphoblastic Leukemia (ALL) Guidelines. Medscape. 2015. 1.
Labardini-Méndez JF, Cervera-Cevallos E, López-Navarro OG, Corrales-Alfaro C, Balbuena-Martínez M, Barbosa-Ibarra AA y cols. Leucemia linfoblástica aguda. Oncoguía. Cancerología. 2011; 6: 111-115.
Organización Mundial de Salud. Cáncer. Nota descriptiva Febrero de 2017.
Guzmán-Piñeiro R, Barceló-Pérez C, Taureaux-Díaz N, Reyes-Secades G. Moncada-Rodríguez I. Estudio caso-control sobre factores de riesgo de la leucemia infantil en Ciudad de La Habana. Rev Cub Hig Epidemiol. 2007; 45 (1): 1.
Hernández-Morales AL, Zonana-Nacach A, Zaragoza-Sandoval VM. Factores asociados a leucemia aguda en niños. Estudio de casos y controles. Rev Med Inst Mex Seguro Soc. 2009; 47 (5): 497-503.
Does M, Scélo G, Metayer C, Selvin S, Kavet R, Buffler P. Exposure to electrical contact currents and the risk of childhood leukemia. Radiant Res. 2011: 1-15.
Flores-López G, Méndez-Hernández P, Cuacenetl-Jiménez JJ, Rojas-Lim E, Nava-Cruz CB, Mauricio-García JF y cols. Riesgos ambientales y alimentarios en niños y adolescentes con diagnóstico de leucemia en Tlaxcala. Rev Sal Quintana Roo. 2015; 8 (31):12-16.
Lara-Rodríguez D, Fing-Soto EA. Evaluación del estado nutricional de niños y adolescentes con leucemia linfoblástica aguda en el Hospital General de Celaya. Bol Clin Hosp Infant Edo Son. 2012; 29 (1): 19-23.
Estrada-Padilla SA, Corona-Rivera JR, Sánchez-Zubieta F, Bobadilla-Morales L, Corona-Rivera A. Variantes fenotípicas en pacientes con leucemia linfoblástica del occidente de México. An Pediat. 2015; 82 (2): 76-77.
De La Chica RA, Solé F. Posible relación entre la exposición prenatal al Tabaco y cáncer hematológico en niños. Hospital Del Mar. Diagn Prenat. 2011; 22 (1): 14-19.