Estrada RAE, Zomosa SVC

Language: Spanish
References: 23
Page: 2-11
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ABSTRACT

Amyloid β-peptide (Aβ) is related to Alzheimer Disease (AD) and is the main component of the amyloid plaques. The variants of Aβ peptide are Aβ (1-40), (1-42) and (25-35), which is the most toxic region and plays an important role in the disease. In this work, the molecular origins, conformational change and biological activity of Aβ peptide are reviewed to provide a better picture at the molecular level of AD.

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