Estrada RAE, Zomosa SVC

Idioma: Español
Referencias bibliográficas: 23
Paginas: 2-11
Archivo PDF: 665.44 Kb.

RESUMEN

El péptido β-amiloide (Aβ) está relacionado con la enfermedad de Alzheimer (EA) y es el principal componente de las placas amiloides. Las variantes del péptido Aβ son Aβ (1-40), (1-42) y (25-35), que es la región más tóxica y juega un papel relevante en la EA. En este trabajo se revisan los orígenes moleculares, cambios conformacionales y actividad biológica del péptido para proveer un panorama a nivel molecular de la EA.

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