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Federación Mexicana de Ginecología y Obstetricia, A.C.

2017, Number 06

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Ginecol Obstet Mex 2017; 85 (06)

Ovarian cancer with skin metastases. A case report and literature review

Valdespino-Castillo V, Rivera-Hernández M, Maytorena-Córdova G, Cota-Vizcarra A, Blas-Hernández P, Valdespino-Gómez V

Language: Spanish
References: 14
Page: 391-395
PDF size: 316.70 Kb.


ABSTRACT

Background: 80% of the cases of epithelial ovarian cancer are diagnosed in stages III and IV, locoregional recurrence is a frequent feature of this malignant neoplasm. Associated mortality is one of the most important of all malignant neoplasms in women, all over the world.
Objetive: To document the metastasis of ovarian cancer to skin, incidence, clinical presentation, and prognosis.
Clinic case: 67-year-old patient with papillary serous carcinoma stage IIIC of ovary; Optimal surgery and four cycles of chemotherapy (carboplatin and paclitaxel) were performed, with a 21-month disease-free interval. The patient had unexplained papules and nodules on the skin of the abdomen and legs. Incisional biopsy documented relapse to the skin, with no other site of distant metastases. The patient received systemic palliative treatment.
Conclusions: Cutaneous metastases from ovarian cancer have a pleomorphic clinical presentation and widespread distribution throughout the body, often affecting the abdominal or thoracic region; cutaneous ovarian metastases imply a limited life expectancy, despite systemic treatment.


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