2017, Number 4
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Rev Med MD 2017; 8.9 (4)
Neurocutaneous melanosis
Márquez-Palacios RE, Fajardo-Fregoso BF, Chávez-Castillo M, Gálvez-López AG, Ceja-Moreno H, Avilés-Martínez KI
Language: Spanish
References: 8
Page: 182-186
PDF size: 864.07 Kb.
ABSTRACT
Neurocutaneous melanosis is characterized by proliferation of melanocytes and melanin deposits in central nervous
system associated to giant melanocytic nevus. We present the case of a 3 year old male previously healthy with the
presence of cutaneous nevi in different localizations which presented with progressive headache and alteration in
mental status in which infiltration of melanin to central nervous system was documented.
REFERENCES
Viana A, Gontijo B, Bittencourt F. Giant congenital melanocytic nevus. Anais Brasileiros de Dermatologia. 2013;88(6):863-878.
Kadonaga J, Frieden I. Neurocutaneous melanosis: Definition and review of the literature. Journal of the American Academy of Dermatology. 1991;24(5):747- 755.
Bekiesinska-Figatowska M, Szczygielski O, Boczar M. Neurocutaneous melanosis in children with giant congenital melanocytic nevi. Clinical Imaging. 2014;38(2):79-84.
Acosta F, Barkovich A, Frieden I. Neurocutaneous melanosis presenting with hydrocephalus. Journal of Neurosurgery: Pediatrics. 2005;102(1):96-100.
Chen Y, Woodley-Cook J, Sgro M. Sonographic and magneti cresonance imaging findingsof neurocutaneous melanosis. Radiology Case Reports. 2016;11(1):29-32.
Küsters-Vandevelde H, Willemsen A, Groenen P. Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor. Acta Neuropathologica Communications. 2014;2(1).
van Engen-van Grunsven A, Rabold K, Küsters- Vandevelde H. Copy number variations as potential diagnostic and prognostic markers for CNS melanocytic neoplasms in neurocutaneous melanosis. Acta Neuropathologica. 2016;133(2):333- 335.
8 . Pavlidou E, Hagel C, Papavasilliou A. Neurocutaneous Melanosis: Report of Three Cases and Up-to-date Review. Journal of Child Neurology. 2008;.(2): 256-258.