Zepeda-Romero LC, Gutiérrez-Padilla JA, Aguilar-Rodríguez F, Muñoz-Ruvalcaba DK, Pérez Rulfo-Ibarra D, Márquez-González RM, Aguilar-Jiménez IS

Language: Spanish
References: 16
Page: 159-164
PDF size: 1024.76 Kb.

ABSTRACT

Introduction. Angiography used with fluorescein is a powerful tool in the evaluation of retina pathologies, especially because it allows a complete visualization of vascular alterations. Even though this technique has been used to describe alterations in retinopathy of prematurity before, it has not been used to describe findings in the posterior pole. This study was presented with the objective to describe findings in angiography with fluorescein in retinopathy of prematurity in the posterior pole, which are not commonly visualized in indirect ophthalmoscopy.
Material and Methods. Cases of retinopathy of prematurity were selected from neonatal intensive care unit to be submitted to an ophthalmic evaluation under general intravenous anesthesia before laser photocoagulation. Maximal pupillary dilation was achieved with ophthalmic drops containing tropicamide 0.8% and fenilefrine 5% in both eyes. An angiography equipped with RetCamll was used to take image sin high color definition and to perform the angiography with fluorescein intravenously at 10%.
Results. The series was composed of 7 patients that were over 35 weeks in gestational age. Changes in the posterior pole, such as aneurysms, vascular threads, macular edema, pre-retinal fibrovascualar red, capillary dilation and occlusions.
Discussion. Changes in the posterior pole were present in patients with advanced retinopathy of prematurity, which were identified through angiography. This allows for a better comprehension and evaluation of the pathology.

REFERENCES

1. Cantolino SJ, O'Grady GE, Herrera JA et al. Ophthalmoscopic monitoring of oxygen therapy in premature infants. Fluorescein angiography in acute retro lental fibroplasia. Am J Ophthalmol 1971;72(2):322-31

2. 2.Lepore D, Molle F, Pagliara MM, et al. Atlas of fluorescein angiographic findings in eyes undergoing laser for retinopathy of prematurity. Ophthalmology 2011;118(1):168-75

3. 3.Purcaro V, Baldascino A, Papacci P, et al. Fluorescein angiography and retinal vascular development in premature infants. J Matern Fetal Neonatal Med. 2012;26(15):1563

4. 4.Guagliano R, Barillà D, Bertone C, et al. Fluorescein angiography-based diagnosis for retinopathy of prematurity: expert-non expert comparison. Eur J Ophthalmol 2013;23(6):881-886.

5. 5.Ze peda-Romero LC, Oregon-Miranda AA, Lizarraga-Barrón DS, et al. Early retinopathy of prematurity findings identified with fluorescein angiography. Graefes Arch Clin Exp Ophthalmol 2013;251(9):2093-7.

6. 6.Yokoi T, Hiraoka M, Miyamoto M, et al. Vascular abnormalities in aggressive posterior retinopathy of prematurity detected by fluorescein angiography. Ophthalmology 2009;116(7):1377-82.

7. 7.Ng EY, Lanigan B, O'Keefe M. Fundus fluorescein angiography in the screening for and management of retinopathy of prematurity. J Pediatr Ophthalmol Strabismus 2006;43(2):85-90.

8. 8.Azad R, Chandra P, Khan MA, et al. Role of intravenous fluorescein angiography in early detection and regression of retinopathy of prematurity. J Pediatr Ophthalmol Strabismus 2008;45(1):36-9.

9. 9.Wallace DK, Kylstra JA, Greenman DB, et al. Significance of isolated neovascular tufts ("popcorn") in retinopathy of prematurity. J AAPOS 1998;2(1):52-6.

10. Hindle NW. Whatis pop corn? JA APOS 1998;2(4):193-4.

11. 11.Maldonado RS, O'Connell R, Ascher SB, et al. Spectral-domain optical coherence tomographic assessment of severity of cystoid macular edema in retinopathy of prematurity. Arch Ophthalmol. 2012;130(5):569-78. Erratum in: Arch Ophthalmol. 2012;130(8):1059.

12. 12.Chavala SH, Farsiu S, Maldonado R, et al. Insights into advanced retinopathy of prematurity using handheld spectral domain optical coherence tomography imaging. Ophthalmology 2009;116(12):2448-56.

13. 13.Lee AC, Maldonado RS, Sarin N, et al. Macular features from spectral-domain optical coherence tomography as an adjunct toindirect ophthalmoscopy in retinopathy of prematurity. Retina 2011;31(8):1470-82.

14. 14.Flynn JT, Chan-Ling T. Retinopathy of prematurity: two distinct mechanisms that underlie zone 1 and zone 2 disease. Am J Ophthalmol 2006;142(1):46-59.

15. 15.Scanlon PH, Stratton IM, Histed M, et al. The influence of background diabetic retinopathy in the second eye on rates of progression of diabetic retinopathy between 2005 and 2010. Acta Ophthalmol 2013;91(5):e335-9.

16. 16.Zepeda-Romero LC, Gutierrez-Padilla JA, De la Fuente-Torres MA, Angulo-Castellanos E, Ramos- Padilla E, Quinn GE. Detection and treatment for retinopathy of prematurity in Mexico: need for effective programs. JAAPOS. 2008;12(3):225-6