2017, Number 1
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Rev Sanid Milit Mex 2017; 71 (1)
Treatment of acute anteroapical ST elevation myocardial infarction not reperfused Killip and Kimbal class III by splinting of anterior descending artery with stent
Gutiérrez-Leonard H, Fuentes-Córdova BA, Galván-Vargas CG, Cabrera-Arroyo CG, Meneses-Bonilla A, Hernández-Casas AS
Language: Spanish
References: 31
Page: 31-41
PDF size: 350.43 Kb.
ABSTRACT
Background: Acute heart failure as a complication of acute
anteroapical ST elevation myocardial infarction is the most frequent
complication and Is the first cause of death in the acute and chronic
phase. At present, medical pharmacological treatment has been
improved and guidelines have been proposed for the management
of these patients who have a good evolution, but a non negligible
percentage of patients have refractory heart failure, hemodynamic
instability, pulmonary congestion, which implies a longer hospital
stay and nosocomial infections.
Objective: To reduce mortality of acute anteroapical ST elevation
myocardial infarction not reperfused Killip and Kimbal class III.
Materials and methods: We included patients attended at the
Hospital Central Militar interventional cardiology department, with
the diagnosis of acute anteroapical ST elevation myocardial infarction
not reperfused. The infarct was classified as Killip and Kimbal class III
with decreased ejection fraction and after 72 hours of optimal medical
treatment for heart failure, persisted in the Killip and Kimbal class III.
Coronary angiography and ventriculography were performed, finding
total obstruction of the anterior descending artery and akinesia,
dyskinesia or anteroapical left ventricular aneurysm. The technique
of splinting of anterior descending artery with stents was performed in
the hemodynamic laboratory. Their management was continued in the
coronary care unit. Transthoracic echocardiography was performed 8
days after the intervention.
Results: A total of 21 patients who met the selection criteria were
included. The ejection fraction of the left ventricle prior to the procedure
was on average 29%. Five subjects developed cardiogenic
shock in the first twelve hours of hospitalization, but only one died.
Of the remaining subjects, two additional deaths were observed, none
at an early age (first 30 days). The 30-day survival was 95.2%, with a
median survival of 29.76 days (95% CI 29.3, 30.2).
Conclusion: In patients with acute anteroapical ST elevation
myocardial infarction not reperfused Killip and Kimbal class III with
reduced left ventricular ejection fraction (less than 35%) and akinesia dyskinesia-apical aneurysm, the technique of splinting of anterior descending artery with stents was associated with a better prognosis
with a 30-day survival rate was 95.2%, with a median survival of
29.76 days (95% CI 29.3, 30.2), with a significant improvement in
left ventricular ejection fraction (previous 30.5 + 6.4% , posterior 33.3 + 6.5%, p = 0.016).
REFERENCES
Thygesen K, Alpert JS, White HD. Universal definition of myocardial infarction. Eur Heart J. 2007;28:2525-2538.
Worner F, Viles D, Díez-Aja S. Epidemiología y pronóstico de la insuficiencia cardiaca postinfarto. Rev Esp Cardiol. 2006;6(Suppl 2):3B-14B.
Steg G, James SK, Atar D, Badano Luigi P, Lundqvist CB, Borger MA, et al. Guía de Práctica Clínica de la ESC para el manejo del infarto agudo de miocardio en pacientes con elevación del segmento ST. Rev Esp Cardiol. 2013;66(1):53.e1-e46.
Torabi A, Cleland JGF, Khan NK, Loh PH, Clark AL, Alamgir F, et al. The timing of development and subsequent clinical course of heart failure after a myocardial infarction. Eur Heart J. 2008;29(7):859-870.
Velázquez EJ, Francis GS, Armstrong PW, Aylward PE, Díaz R, O'Connor CM, et al. An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry. Eur Heart J. 2004;25(21):1911-1919.
Grancelli H, Zambrano C, Dran D, Ramos S, Soifer S, Buso A, et al. Cost-effectiveness analysis of a disease management program in chronic heart failure. DIAL Trial, GESICA Investigators. JACC 2003; 41:517 (abstract)
Lindholm MG, Kober L, Boesgaard S, Torp-Pedersen C, Aldershvile J. Trandolapril Cardiac Evaluation study group. Cardiogenic shock complicating acute myocardial infarction; prognostic impact of early and late shock development. Eur Heart J. 2003;24(3):258-265.
Cleland JG, Torabi A, Khan NK. Epidemiology and management of heart failure and left ventricular systolic dysfunction in the aftermath of a myocardial infarction. Heart 2005;91(Suppl II):ii7–ii13.
Hellermann JP, Goraya TY, Jacobsen SJ, Weston SA, Reeder GS, Gersh BJ, et al. Incidence of heart failure after myocardial infarction: is it changing over time? Am J Epidemiol. 2003;157(12):1101-1107.
Nieminen MS, Böhm M, Cowie MR, Drexler H, Filippatos GS, Jondeau G, et al. Guías de Práctica Clínica sobre el diagnóstico y tratamiento de la insuficiencia cardíaca aguda. Rev Esp Cardiol. 2005;58(4):389-429.
Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction: experimental observations and clinical implications. Circulation. 1990;81(4):1161-1172.
Zornoff LAM, Spadaro J. Remodelação ventricular após infarto agudo do miocárdio: conceitos, fisiopatologia e abordagem terapêutica. Arq Bras Cardiol. 1997; 68(6): 453-460.
Francis GS. Pathophysiology of chronic heart failure. Am J Med. 2001;110(Suppl 7A):37S-46S.
Matsubara BB, Zornoff LAM. Matriz colágena intersticial e sua relação com a expansão miocárdica no infarto agudo. Arq Bras Cardiol. 1995;64(6):559-563.
Cohn JN, Ferrari R, Sharpe N. Cardiac remodelingconcepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. JACC 2000;35(3):569-582.
Cooley DA, Frazier OH, Duncan JM, Reul GJ, Krajcer Z. Intracavitary repair of ventricular aneurysm and regional dyskinesia. Am Surg 199;215(5):417-423
Brochet E, Czitrom D, Karila-Cohen D, Seknadji P, Faraggi M, Benamer H, et al. Early changes in myocardial perfusion patterns after myocardial infarction: relation with contractile reserve and functional recovery. JACC 1998;32(7):2011-2017.
Galiuto L, Lombardo A, Maseri A, Santoro L, Porto I, Cianflone D, et al. Temporal evolution and functional outcome of no reflow: sustained and spontaneously reversible patterns following successful coronary recanalisation. Heart. 2003;89(7):731-737.
Takano H, Hasegawa H, Nagai T, Komuro I. Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies. Intern Med. 2003;42(6):465-469.
Hale SL, Kloner RA. Left ventricular topographic alterations in the completely healed rat infarct caused by early and late coronary artery reperfusion. Am Heart J. 1988;116:1508-1513.
Wackers FJ, Berger HJ, Weinberg MA, Zaret BL. Spontaneous changes in left ventricular function over the first 24 hours of acute myocardial infarction: implications for evaluating early therapeutic interventions. Circulation. 1882;66:748-754.
Tamaki N, Yasuda T, Leinbach RC, Gold HK, McKusick KA, Strauss HW. Spontaneous changes in regional wall motion abnormalities in acute myocardial infarction. Am J Cardiol. 1986;58(6):406-410.
Warren SE, Royal HD, Markis JE, Grossman W, McKay RG. Time course of left ventricular dilation after myocardial infarction: influence of infarct-related artery and success of coronary thrombolysis. JACC 1988;11:12-19.
Anand IS, Florea VG, Solomon SD, Konstam MA, Udelson JE. Noninvasive assessment of left ventricular remodeling: concepts, techniques and implications for clinical trials. J Card Fail. 2002;8(Suppl 6):S452-464.
Pitt B, Remme W, Zannad F, Neaton J, Martinez F, Roniker B, et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. NEJM 2003;348:1309-1321.
Pfeffer MA, McMurray JJ, Velazquez EJ, Rouleau JL, Køber L, Maggioni AP, et al. Valsartan, captopril or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. NEJM 2003;349:1893-1906.
Shlipak MG, Browner WS, Noguchi H, Massie B, Frances CD, McClellan M. Comparison of the effects of angiotensin converting-enzyme inhibitors and beta blockers on survival in elderly patients with reduced left ventricular function after myocardial infarction. Am J Med. 2001;110:425-433.
Gan SC, Beaver SK, Houck PM, MacLehose RF, Lawson HW, Chan L. Treatment of acute myocardial infarction and 30-day mortality among women and men. NEJM 2000;343:8-15.
Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986;1:397-402.
International Study Group. In-hospital mortality and clinical course of 20,891 patients with suspected acute myocardial infarction randomised between alteplase and streptokinase with or without heparin. Lancet. 1990;336:71-75.
Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, et al. 2013 ACCF/AHA Guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;128(16):e240-e327.