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ISSN 0187-5337 (Print)
Instituto Nacional de Perinatología

2005, Number 3-4

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Perinatol Reprod Hum 2005; 19 (3-4)

Neurodevelopment in infants with congenital hypothyroidism antecedents

Arreola-Ramírez G, Barrera- Reyes RH, Jiménez-Quiroz R, Ramírez TMA, Segura-Cervantes E, Granados-Cepeda ML, Ramírez-Vargas MN, Meza-Rodríguez MP

Language: Spanish
References: 65
Page: 141-151
PDF size: 129.11 Kb.


ABSTRACT

Introduction: Follow-up studies of hypothyroid infants who received early treatment evidence the presence of the same IQ vs. the general population.
Material and methods: Retrospective cohort study. Twenty-four hypothyroid infants detected in neonatal screening were compared to a control group. The newborns were assessed from six months to seven years based on Bayley’s infant development scales (ID), the Terman-Merril IQ (CI) and the learning aptitude of the heard of hearing with the Hiskey-Nebraska test (CA).
Results: Twenty hypothyroid infants showed a normal or high CI or ID. One of the infants with a ID result below the mean, two with an CI below the mean, one hearing impaired infant with low learning aptitude. No differences were found vs. the control group. The use of ototoxic medications, prematurity and hyperbilirubinemia explain the low coefficients between the hypothyroid individuals and the control.
Conclusions: The CI and the ID results in the hypothyroid group who received early treatment showed no difference vs. the control group.


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