2017, Number 1
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Alerg Asma Inmunol Pediatr 2017; 26 (1)
Use of rituximab and intravenous immunoglobulin in the treatment of neuroimmune diseases. Case report
Sosa-Vizcaino A, Scheffler-Mendoza S, Hernández-Bautista VM, Dávila G, Borjas-Aguilar KL, Martínez-Pérez M, Venegas-Montoya E
Language: Spanish
References: 21
Page: 27-32
PDF size: 169.58 Kb.
ABSTRACT
In the last years new pathologies have been described, as well as the association between neurology and immunology, by which it has been proven that diseases with neurological components are triggered by an autoimmune etiology, many of them driven by inflammatory processes generating histological changes, cellular and molecular damage. Understanding the pathophysiological mechanism behind these pathologies can expand the field of treatment. In this article we describe three clinical cases of patients with neurological pathologies with an autoimmune etiology such as myasthenia gravis, myoclonic encephalopathy and autoimmune encephalitis; all three cases were refractory to first line management and due to clinical evolution they required the use of monoclonal antibodies and intravenous human immunoglobulin resulting in clinical improvement.
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