Alert SJ, Alfonso ED, Ropero TR

Language: Spanish
References: 23
Page: 4-10
PDF size: 78.70 Kb.

ABSTRACT

Introduction: in the treatment of the central nervous system tumors in children and adolescents, the irradiation plays a fundamental role in their future evolution. Recurrence frequently occurs for which treatment does not provide many management possibilities. These patients have undergone several treatments such as surgery, polychemotherapy and reirradiation.
Objective: to show the results achieved in children and adolescents who were reirradiated at the National Institute of Oncology and Radiobiology in Havana.
Methods: a retrospective, randomized study was conducted in twelve children and adolescents aged 9 to 18 years, with central nervous system tumor recurrences and irradiated with a linear accelerator, 3D planning and at a variable dose of 36-56 Gy.
Results: all the patients responded to treatment, with survival rates of 59.7 and 31.8 % at 12 and 24 months, respectively. The survival time median was 13.4, 95 % CI (5.0-21.8) months. Five patients are still alive.
Conclusions: reirradiation could be a choice to be considered in the relapsed tumors as a palliative therapy to extend survival time and to improve life quality.

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