Viesca-Contreras V, Amatón-Tabares R, Duque-Rodríguez J

Language: Spanish
References: 21
Page: 113-118
PDF size: 1058.07 Kb.

ABSTRACT

Acquired Hemophilia is a rare immune hemorrhagic coagulopathy, secondary to the appearance of circulating autoantibodies in plasma, called inhibitors, leading to hemorrhagic manifestations in previously healthy individuals. It is a complex, rarely suspected pathology whose initial manifestations are unclear and may not be detected early. Symptoms in general are related to spontaneous bleeding in the skin, muscles, soft tissues and mucous membranes. The most common type is secondary to coagulation factor VIII inhibitors. It is a disease with a high mortality rate without adequate treatment. The basis of the diagnosis is the detection of low concentrations of FVIII and the presence in plasma of an inhibitor whose action depends on the time. We report the case of a 22-year-old female patient who had a compartment syndrome on the left hand due to severe subcutaneous bleeding, requiring fasciotomies that caused persistent hemorrhage and severe hypovolemic shock.

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