Acquired myasthenia gravis in domestic canines

Maritere González Lama; Francisco J. Trigo Tavera

2000, Number 3

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Vet Mex 2000; 31 (3)

**Acquired myasthenia gravis in domestic canines**

González LM, Trigo TFJ

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Language: English/Spanish
References: 41
Page: 231-238
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ABSTRACT

The importance of acquired myasthenia gravis is described as a not rare disorder in veterinary medicine, being a common cause of acquired megaesophagus. Normal physiology of neuromuscular junction, pathophysiology, classification, signalment, diagnosis, treatment and prognosis are discussed. Controversies about its treatment, prognosis and the relevance of not subdiagnosing this disease are analyzed.

REFERENCES

1. Krotje LJ, Fix AS, Potthoff AD. Acquired myasthenia gravis and chollangiocellular carcinoma in a dog. J Am Vet Med Assoc 1990;199:488-490.
2. Gaynor AR, Shofer FS, Washabau RJ. Factors for acquired megaesophagus in dogs. J Am Vet Med Assoc 1997;211:1 406-1 412.
3. Yam PS, Shelton GD, Simpson JW. Megaoesophagus secondary to acquired myasthenia gravis. J Small Anim Pract 1996;37:179-183.
4. Holland CT, Shelton GD, Satchell PM, Farrow BRH. Antibodies to nicotinic acetylcholine receptors in dogs with megaoesophagus. Austr Vet J 1994;71:221-222.
5. Birchard SJ, Sherding RG. Manual clínico de pequeñas especies. Vol II. México (DF): McGraw-Hill-Interamericana,1996.
6. Van Ham LML. A myasthenic-like syndrome in young related mongrel dogs. Prog Vet Neurol 1992;3:135-139.
7. Flagstad A, Trojaborg W, Gammeltoft S. Congenital myasthenic syndrome in the dog breed Gammel Dansk Honsenhund: clinical, electrophysiological, pharmacological and immunological comparison with acquired myasthenia gravis. Acta Vet Scand 1989;30:89-102.
8. Kirk RW, Bonagura JD. Terapéutica veterinaria de pequeños animales. Vol XI. Madrid, España: Interamericana, 1994.
9. Ettinger SJ. Textbook of veterinary internal medicine. 4th ed. Philadelphia: W. B. Saunders Co., 1995.
10. Tilley LP, Smith FWK, MacMurray AC. La consulta veterinaria canina y felina en 5 minutos. Buenos Aires, Argentina: Intermédica, 1998.
11. Chrisman CL. Problems in small animal neurology. 2nd ed. Philadelphia: Lea and Febiger, 1991.
12. Lorenz, JE Oliver MD. Handbook of veterinary medicine. 2nd ed. Philadelphia: W.B. Saunders Co., 1993.
13. Nelson RW, Couto CG. Small animal internal medicine. 2nd ed. St. Louis (Mo): Mosby Co., 1998.
14. Joseph RJ, Carrillo JM, Lennon VA. Myasthenia gravis in the cat. J Vet Int Med 1988;2:75-79.
15. Dewey CW. Acquired myasthenia gravis in dogs. Part I. Comp Cont Edu Pract Vet 1997;19:1340-1354.
16. Webb AA, Taylor SM, Mcphee L. Focal myasthenia gravis in a dog. Can Vet J 1997;38:493-495.
17. King LG, Vite ChH. Acute fulminating myasthenia gravis in five dogs. J Am Vet Med Assoc 1998;212:830-834.
18. Dewey CW, Bailey CS, Shelton GD, Kass PH, Cardinet GH. Clinical forms of acquired myasthenia gravis in dogs: 25 cases (1988-1995). J Vet Int Med 1997;11:50-57.
19. Schütt I, Kersten U. Myasthenia gravis. Un resumen sobre el desarrollo de la enfermedad en 23 casos. Rev Vet Buenos Aires 1993;74:190-192.
20. Hopkins AL. Canine myasthenia gravis. J Small Anim Pract 1992;33:477-484.
21. Shelton GD, Willard MC, Cardinet CG, Lindstrom J. Acquired myasthenia gravis. Selective involvement of esophageal, pharyngeal, and facial muscles. J Vet Int Med 1990;4:281-284.
22. Lefebvre H. Myasthénie grave acquise chez les carnivores domestiques. Point Vet 1990;22:13-21.
23. Beddow B. Myasthenia gravis in a dog. Vet Rec 1990; 127:244.
24. Poncelet L, Balligand M, Jakovljevic S. Myasthénie grave acquise chez un chien: diagnostic différentiel. Point Vet 1989;21:51-55.
25. Watson P. What is your diagnosis? (Myasthenia gravis in a dog). J Small Anim Pract 1994;35:284-332.
26. Lewis RM. Immune-mediated muscle disease. Vet Clin North Am: Small Anim Pract 1994;24:703-706.
27. Berry WL. Episodic weakness in dogs. Cont Edu 1990;12:141-153.
28. Scott-Moncrieff JC, Hawkins EC, Cook JR. Canine muscle disorders. Comp Cont Edu Pract Vet 1990;12:31-34.
29. Shelton GD, Schule A, Kass PH. Risk factors for acquired myasthenia gravis in dogs: 1,154 cases (1991-1995). J Am Vet Med Assoc 1997;211:1 428-1 431.
30. González LM. Miastenia gravis generalizada, reporte de un caso clínico. Memorias de las Primeras Jornadas Médicas y Curso en Temas Selectos en Gastroenterología en Perros y Gatos; mayo, 1999; Toluca, Edo. de México. Universidad Autónoma del Estado de México; Toluca, Edo. de México: 1999.
31. Guyton AC. Textbook of medical physiology. 8th ed. Philadelphia: W. B. Saunders Co., 1991
32. Despopoulos A, Silbernagl S. Color atlas of physiology. 4th ed. New York: Thieme Medical Publishers, 1991.
33. Day MJ. Review of thymic pathology in 30 cats and 36 dogs. J Small Anim Pract 1997;38:393-403.
34. Rusbridge C, White RN, Elwood CM, Wheeler SJ. Treatment of acquired myasthenia gravis associated with thymoma in two dogs. J Small Anim Pract 1996;36:376-380.
35. Lainesse MFC, Taylor SM, Myers SL, Haines D, Fowler JD. Focal myasthenia gravis as a paraneoplastic syndrome of canine thymoma: improvement following thymectomy. J Am Anim Hosp Assoc 1996;32:111-117.
36. Atwaterm SW, Powers BE, Park RD, Straw RC, Ogilvie GK, Withrow SJ. Thymoma in dogs: 23 cases (1980-1991). J Am Vet Med Assoc 1994;205:1 007-1 013.
37. Dewey CW. Acquired myasthenia gravis in dogs. Part II. Comp Cont Edu Pract Vet 1998;20:47-59.
38. Plumb DC. Veterinary drug handbook. 2nd ed. Ames (Io): Iowa State University Press, 1995.
39. Hackett TB, Van Pelt DR, Willard MD, Martin LG, Wingfield WE. Third degree atrioventricular block and acquired myasthenia gravis in four dogs. J Am Vet Med Assoc 1995;206:1 173-1 176.
40. Bartges JW, Klausner JS, Bostwick EF, Hakala JE, Lennon VA. Clinical remission following plasmapheresis and corticosteroid treatment in a dog with acquired myasthenia gravis. J Am Vet Med Assoc 1990;196:1 276-1 278.
41. Washabau RJ, Hall JA. Gastrointestinal prokinetic therapy: serotonergic drugs. Cont Edu 1997;19:473-479.