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Federación Mexicana de Ginecología y Obstetricia, A.C.

2016, Number 03

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Ginecol Obstet Mex 2016; 84 (03)

Maternal complications in preeclamptic patients with hyperuricemia managed in Intensive Care Unit

Vázquez-Rodríguez JG, Rico-Trejo EI

Language: Spanish
References: 30
Page: 143-149
PDF size: 320.58 Kb.


ABSTRACT

Background: Hyperuricemia is a factor related to a higher frequency of complications in patients with preeclampsia.
Objetives: To determine maternal complications in preeclamptic patients with hyperuricemia managed in the intensive care unit of a high-specialty hospital.
Material and Methods: Cross-sectional study. Clinical files of 127 preeclamptic patients with criteria of severe disease were reviewed. Maternal complications were studied only in patients with hyperuricemia defined as a serum uric acid (UA) level › 4 mg/dL upon admission. Descriptive statistics were used.
Results: Frequency of patients with hyperuricemia was 88.1% (112 cases). Median value of UA was 6.6 ± 1.5 mg/dL (range 4.6-12.4), maternal age 28.1 ± 5.98 years, parity 2 and gestational age 32.9 ± 3.7 weeks. Cesarean section was performed in 98.21%. Frequency of maternal complications was 50% (56 cases): HELLP syndrome 40.1% (45 cases), acute renal injury 6.2% (7 cases), abruptio placentae 1.7% (2 cases), hemorrhage due to uterine atony 0.8% (1 case) and acute pulmonary edema 0.8% (1 case). There were no cases of multiorgan failure syndrome and maternal mortality was 0%. None of the patients experienced worsening of their condition.
Conclusions: There was an elevated frequency of patients with hyperuricemia and maternal complications. Reported complications were different from those reported in previous studies. All patients were successfully intervened with the administered medical treatment and may be a reflection of the beneficial effect of intensive care treatment.


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