Rojas GP, Martínez MÁ, Márquez EC, Gutiérrez SE, Szydlo-Shein G

Language: Spanish
References: 25
Page: 74-81
PDF size: 414.48 Kb.

ABSTRACT

We analyzed and compared the effectiveness of n-2-butyl cyanoacrylate to avoid seroma formation in abdominal flap dissection in 40 Wistar adult rats, divided into 4 groups. The abdominal dissection measured 4.5 × 4.5 cm. The difference between each group had to do with the way dead space closed. Four groups were created: Group 1 was the control group, in which the abdominal flap was dissected and the space was closed using conventional procedures. In group 2 the dead space was closed using N-butyl-2-cyanoacrylate, while in group 3 fibrin sealant was used and in group 4, fifteen silk points were given simulating the progressive tension technique. The rats were sacrificed seven days after surgery and the presence of seroma was evaluated as well as surgical time and costs. Group 1 showed a higher probability for seroma formation (p = 0.009). Surgical time was noticeably longer in group 4 when compared with the other groups (p ‹ 0.001). We concluded that the application of N-butyl-2 cyanoacrylate for closing dead space in abdominal flaps is a safe, quick, effective and inexpensive technique when compared with others.

REFERENCES

1. Bercial ME, Sabino Neto M, Calil JA, Rossetto LA, Ferreira LM. Suction drains, quilting sutures, and fibrin sealant in the prevention of seroma formation in abdominoplasty: which is the best strategy? Aesth Plast Surg 2012; 36: 370-373.

2. Walgenbach KJ, Bannasch H, Kalthoff S, Rubin JP. Randomized, prospective study of tissuglu surgical adhesive in the management of wound drainage following abdominoplasty. Aesth Plast Surg 2012; 36: 491-496.

3. Gilbert TW, Badylak SF, Beckman EJ, Clower DM, Rubin JP. Prevention of seroma formation with TissuGlu surgical adhesive in a canine abdominoplasty model: Long term clinical and histologic studies. J Plast Reconstr Aesth Surg 2013; 66: 414-422.

4. Gilbert TW, Badylak SF, Gusenoff J, Beckman EJ, Clower DM, Daly P, Rubin JP. Lysine-derived urethane surgical adhesive prevents seroma formation in a canine abdominoplasty model. Plast Reconstr Surg 2008; 122: 95-102.

5. González JM. Cianoacrilato. Definición y propiedades. Toxicidad y efectos secundarios. Aplicaciones en medicina y odontología. Odontoestomatol 2012; 28 (2): 95-102.

6. Kukleta JF, Freytag C, Weber M. Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using N-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. Hernia 2012; 16: 153-162.

7. Mobley S, Hilinski J, Toriumi D. Surgical tissue adhesives. Facial Plast Surg Clin North Am 2002; 10: 147-154.

8. Baroudi R, Ferreira CA. Seroma: how to avoid it and how to treat it. Aesth Surg J 1998; 18: 439-441.

9. Le Louarn C, Pascal JF. The high-superior-tension technique: evolution of lipoabdominoplasty. Aesth Plast Surg 2010; 34: 773-781.

10. Andrades P, Prado A, Danilla S, Guerra C, Benitez S, Sepulveda S, Sciarraffia C, De Carolis V. Progressive tension sutures in the prevention of postabdominoplasty seroma: a prospective, randomized, double-blind clinical trial. Plast Reconstr Surg 2007; 120 (4): 935-946.

11. Srivastava V, Basu S, Shukla VK. Seroma formation after breast cancer surgery: what we have learned in the last two decades. J Breast Cancer 2012; 15 (4): 373-380.

12. Shin IS, Lee DW, Lew DH. Efficacy of quilting sutures and fibrin sealant together for prevention of seroma in extended Latissimus dorsi flap donor sites. Arch Plast Surg 2012; 39-509-513.

13. Bold EL, Wanamaker JR, Zins JE, Lavertu P. The use of fibrin glue in the healing of skin flaps. Am J Otolaryngol 1996; 17 (1): 27-30.

14. Cha HG, Kang SG, Shin HS, Kang MS, Nam SM. Does fibrin sealant reduce seroma after immediate breast reconstruction utilizing a Latissimus dorsi myocutaneous flap? Arch Plast Surg 2012; 39: 504-508.

15. Pollock TA, Pollock H. No-drain abdominoplasty with progressive tension sutures. Clin Plast Surg 2010; 37: 515-524.

16. Pollock H, Pollock T. Progressive tension sutures: a technique to reduce local complications in abdominoplasty. Plast Reconstr Surg 2000; 105 (7): 2583-2586.

17. Nahas FX, Ferreira LM, Ghelfond C. Does quilting suture prevent seroma in abdominoplasty? Plast Reconstr Surg 2007; 119 (3): 1060-1064.

18. Carless PA, Henry DA. Systematic review and meta-analysis of the use of fibrin sealant to prevent seroma formation after breast cancer surgery. Br J Surg 2006; 93: 810-819.

19. Miri Bonjar MR, Maghsoudi H, Samnia R, Saleh P, Parsafar F. Efficacy of fibrin glue on seroma formation after breast surgery. Int J Breast Cancer 2012; 2012: 643132.

20. Jain PK, Sowdi R, Anderson AD, MacFie J. Randomized clinical trial investigating the use of drains and fibrin sealant following surgery for breast cancer. Br J Surg 2004; 91: 54e60.

21. Moore M, Burak WE Jr, Nelson E, Kearney T, Simmons R, Mayers L et al. Fibrin sealant reduces the duration and amount of fluid drainage after axillary dissection: a randomized prospective clinical trial. J Am Coll Surg 2001; 192 (5): 591-599.

22. Langer S, Guenther JM, DiFronzo LA. Does fibrin sealant reduce drain output and allow earlier removal of drainage catheters in women undergoing operation for breast cancer? Am Surg 2003; 69 (1): 77-81.

23. Rodby KA, Stepniak J, Eisenhut N, Lentz CW 3rd. Abdominoplasty with suction undermining and plication of the superficial fascia without drains: a report of 113 consecutive patients. Plast Reconstr Surg 2011; 128 (4): 973-981.

24. Sözen S, Topuz O, Tükenmez M, Keçeli M. The use of fibrin sealant after total thyroidectomy for benign disease obviates the need for routine drainage. Results of a randomized controlled trial. Hippokratia 2011; 15 (3): 247-251.

25. Elmeligy A, Sadek E, El-Sherbiny K. Using of octyl-2-cyanoacrylate in total ear reconstruction: avoidance of suturing and suction. Egypt J Plast Reconstr Surg 2010; 34 (1): 89-93.