2016, Number 6
<< Back Next >>
Rev Med Inst Mex Seguro Soc 2016; 54 (6)
Quality of corneal tissue procured by trained non-ophthalmologist medical personnel
Verdiguel-Sotelo K, Carrasco-Quiroz A, López-Macías PA, Ortiz-Lerma R
Language: Spanish
References: 40
Page: 688-695
PDF size: 277.73 Kb.
ABSTRACT
Background: The cornea is the first tissue awaiting transplantation at
a national level. It is imperative to train health personnel in procurement
technique with excision of corneoscleral button in situ.
The objective was to compare the quality of corneal tissue procured by
social service medical interns and Ophthalmology residents in a third
level hospital.
Methods: We performed a quasi-experimental pilot study with two
groups: group 1, which included trained social service medical interns,
and group 2, which included trained residents of Ophthalmology.
Results: 10 participants in two groups had a mean endothelial cell density
of 2662.35 ± 223.92, a percentage of hexagonal cells of 53.89 ± 5.61 %,
and a coefficient of variation of 0.43 ± 0.06 in group 1; also, and respectively,
group 2 presented these results: 2656.44 ± 156.14, 64.15 ± 5.90 %,
and 0.45 ± 0.06. The macroscopic and microscopic quality of procured
corneal tissues was similar in both groups. Besides the learning curve
and complications were minimal.
Conclusion: All trained medical personnel acquired skills necessary to
obtain optimal corneal tissue
REFERENCES
Nishida T, Saika S. Cornea and Sclera: Anatomy and Physhiology. En: Krachmer JH, Mannis MJ, Holland EJ (eds.). Cornea. Fundamentals, Diagnosis and management. 3rd edition, USA: Elsevier; 2011.
Cunningham WJ, Brookes NH, Twohill HC, Moffatt SL, Pendergrast DG, Stewart JM, et al. The New Zealand National Eye Bank Study: Trends in the Acquisition and Storage of Corneal Tissue over the Decade 2000 to 2009. Clin Experiment Ophthalmol. 2012 Mar;40(2):141-7. doi: 10.1111/j.1442- 9071.2011.02681.x. Epub 2011 Nov 4.
Piñero Llorens DP, Plaza Puche AB. Análisis comparativo del estudio morfológico del endotelio corneal mediante dos microscopios especulares: CSO y Noncom Robo. Gaceta Óptica. 2009;(436):42-6.
Joyce NC. Cell cycle status in human corneal endothelium. Exp Eye Res. 2005 Dec;81(6):629-38. Epub 2005 Jul 28.
Bourne WM, Nelson LR, Hodge DO. Central corneal endothelial cell changes over a ten-year period. Invest Ophthalmol Vis Sci. 1997 Mar;38(3):779-82.
Rootman DB, Wankiewicz E, Sharpen L, Baxter SA. In situ versus whole-globe harvesting of corneal tissue from remote donor sites: effects on initial tissue quality. Cornea. 2007 Apr;26(3):270-3.
Schroeter J, Wilkemeyer I, Herrlinger F, Pruss A. Comparison of in situ Corneoscleral Disc Excision versus Whole Globe Enucleation in Cornea Donors Regarding Microbial Contamination in Organ Culture Medium – a Prospective Monocentric Study over 9 Years. Transfus Med Hemother. 2012 Dec; 39(6): 391-4. doi: 10.1159/000345717
Elisabeth P, Hilde B, Ilse C. Eye bank issues: II. Preservation techniques: warm versus cold storage. Int Ophthalmol. 2008 Jun; 28(3): 155-63. doi: 10.1007/ s10792-007-9086-1
Duman F, Kosker M, Suri K, Reddy JC, Ma JF, Hammersmith KM, et al. Indications and Outcomes of Corneal Transplantation in Geriatric Patients. Am J Ophthalmol. 2013 Sep;156(3):600-7.e2. doi: 10.1016/j.ajo.2013.04.034.
Sharma N, Agarwal P, Titiyal JS, Kumar C, Sinha R, Vajpayee RB. Optimal Use of Donor Corneal Tissue: One Cornea for Two Recipients. Cornea. 2011 Oct;30(10):1140-4. doi: 10.1097/ ICO.0b013e318209d23c.
Bruinsma M, Lie JT, Groeneveld-van Beek EA, Liarakos VS, van der Wees J, Melles GR. Are Polymegethism, Pleomorphism, and “Poor Swelling” Valid Discard Parameters in Immediate Postmortem Evaluation of Human Donor Corneal Endothelium? Cornea. 2013 Mar;32(3):285-9. doi: 10.1097/ ICO.0b013e318253b1a6.
Lindquist TD, Miller TD, Elsen JL, Lignoski PJ; Policy and Position Research Subcommittee of the Medical Advisory Board of the Eye Bank Association of America. Minimizing the risk of disease transmission during corneal tissue processing. Cornea. 2009 Jun;28(5):481-4. doi: 10.1097/ ICO.0b013e3181907368.
Omar N, Bou Chacra CT, Tabbara KF. Outcome of corneal transplantation in a private institution in Saudi Arabia Clin Ophthalmol. 2013; 7: 1311-8. doi: 10.2147/OPTH.S43719
Croasdale CR, Barney E, Warner EJ. Eye bank tissue utilization between endothelial keratoplasty and penetrating keratoplasty. Cornea. 2013 Mar;32(3):280- 4. doi: 10.1097/ICO.0b013e3182561305.
Price FW Jr, Price DA, Ngakeng V, Price MO. Survey of steroid usage patterns during and after low-risk penetrating keratoplasty. Cornea. 2009 Sep;28(8):865- 70. doi: 10.1097/ICO.0b013e318197ef07.
Gain P, Thuret G, Chiquet C, Rizzi P, Pugniet JL, Acquart S, et al. Cornea procurement from very old donors: post organ culture cornea outcome and recipient graft outcome. Br J Ophthalmol. 2002 Apr; 86(4): 404-11.
García-Alcolea EE. Un nuevo modelo en la formación del oftalmólogo cubano: el modelo experimental. Educac Med Super. 2009; 23(1). [En línea]. Disponible en http://scielo.sld.cu/scielo.php?script=sci_artte xt&pid=S0864-21412009000100006
Randleman JB, Wolfe JD, Woodward M, Lynn MJ, Cherwek DH, Srivastava SK. The resident surgeon phacoemulsification learning curve. Arch Ophthalmol. 2007 Sep;125(9):1215-9.
Kim JH, Kim MJ, Stoeger C, Clover J, Kim JY, Tchah H. Comparison of in situ excision and whole-globe recovery of corneal tissue in a large, single eye bank series. Am J Ophthalmol. 2010 Sep;150(3):427-433. e1. doi: 10.1016/j.ajo.2010.03.021.
Querevalú-Murillo WA. Procuración de córneas por donación Rev Med Inst Mex Seguro Soc. 2010;48(3):233-6.
Centro Nacional de Trasplantes (CENATRA). Estado Actual de Donación y Trasplantes en México 1er Semestre 2013. Distrito Federal, México: CENATRA; 2013. Disponible en http://www.cenatra.salud.gob.mx/ descargas/contenido/trasplante/semestre_2013.pdf
Centro Nacional de Trasplantes (CENATRA). Estado Actual de Donación y Trasplantes en México Anual 2012. Distrito Federal, México: CENATRA; 2012. Disponible en http://www.cenatra.salud.gob.mx/descargas/ contenido/trasplante/reporte_anual_2012.pdf
Molina-Rey DF, Gómez A. Evaluación por décadas de edad del comportamiento de las células endoteliales corneales en población mexicana. Rev Mex Oftalmol. 2005;79(2):93-100.
Jabbar A, Nagpure S. Quality Control of Corneal Tissue Processed and Issued by a Reference Eye Bank. Kerala Journal of Ophthalmology. 2012;24(1):56-60.
Stulting RD, Sugar A, Beck R, Belin M, Dontchev M, Feder RS, et al. Effect of donor and recipient factors on corneal graft rejection. Cornea. 2012 Oct;31(10):1141-7.
Farias RJ, Kubokawa KM, Schirmer M, Sousa LB. [Evaluation of corneal tissue by slit lamp and specular microscopy during the preservation period]. Arq Bras Oftalmol. 2007 Jan-Feb;70(1):79-83.
Van Wijk MJ, Nijenhuis MV, Dorrepaal CA, Bokhorst AG. Factors involved in the occurrence of bleeding complications after enucleation for cornea. Cornea. 2009 Oct;28(9):1014-8. doi: 10.1097/ ICO.0b013e3181a186fc.
Brown S, Small R, Argus B, Davis PG, Krastev A. Early Postnatal discharge from hospital for healthy mothers and term infants (Review). Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet]. This version published: 2009; Review content assessed as up-to-date: November 30, 2008.
Braveman P, Egerter S, Pearl M, Marchi K, Miller C. Problems associated with early discharge of newborn infants. Early discharge of newborns and mothers: a critical review of the literature. Pediatrics. 1995 Oct;96(4 Pt 1):716-26.
Furzan JA. Egreso precoz del recién nacido. Arch Venez Puer Ped. 2007;70(3) (en línea). Disponible en http://www.scielo.org.ve/scielo.php?script=sci_artte xt&pid=S0004-06492007000300004
Malkin JD, Garber S, Broder MS, Keeler E. Infant Mortality and Early Postpartum Discharge. Obstetrics & Gynecology. 2000;96(2):183-8.
Ramírez-Villalobos D, Hernández-Garduño A, Salinas A, González D, Walker D, Rojo-Herrera G, et al. Early hospital discharge and early puerperal complications. Salud Publica Mex. 2009;51(3):212-8. Disponible en http://bvs.insp.mx/rsp/_files/File/2009/ Mayo%20Junio/4-puerperal.pdf
Bravo P, Uribe C, Contreras A. Early postnatal hospital discharge: the consequences of reducing length of stay for women and newborns. Rev Esc Enferm USP. 2011;45(3):758-63. Disponible en: http://www. scielo.br/pdf/reeusp/v45n3/v45n3a30.pdf
American Academy of Pediatrics. Committee on Fetus and Newborn. Hospital Stay for Healthy Term Newborns. Pediatrics. 2010 Feb;125(2):405-9. doi: 10.1542/peds.2009-3119.
Warren JB, Phillipi CA. Care of the Well Newborn. Pediatrics in Review. 2012;33(1):4-18.
Catz C, Hanson JW, Simpson L, Sumner JY. Summary of Workshop: Early Discharge and Neonatal Hyperbilirubinemia. Pediatrics. 1995;96(4)743-5.
Talavera JO. Investigación Clínica. Diseños de Estudio. Rev Med Inst Mex Seguro Soc. 2011;49(1):53-8.
Universidad Tecnológica Nacional (UTN). Tabla de valores críticos de la distribución ji cuadrada. Cátedra de Probabilidad y Estadística. Mendoza, Argentina: Facultad Regional; 2014. Disponible en http://www1.frm.utn.edu.ar/estadistica/documentos/ TD7_JiCuadrada.pdf
Pértegas-Díaz, S, Pita-Fernández S. Cálculo del poder estadístico de un estudio. Unidad de Epidemiologia Clínica y Bioestadística. A Coruña, España: Complexo Hospitalario-Universitario Juan Canalejo. Actualización 20/01/2003. Disponible en https://www.fisterra.com/mbe/investiga/poder_estadistico/ poder_estadistico2.pdf
Lindquist K. How can I estimate relative risk using GLM for common outcomes in cohort studies? Institute for Digital Research and Education, University of California, Los Angeles (UCLA). Disponible en http:// www.ats.ucla.edu/stat/stata/faq/relative_risk.htm