medigraphic.com
Organo Oficial de la Sociedad Mexicana de Urología

2005, Number 2

<< Back Next >>

Rev Mex Urol 2005; 65 (2)

Teratoma importance of non seminomatous testis cancer germ cells (TSTCGC):

Ariza VPJ, Soel EJ, Pilar MM, Pacheco GC, Calderón FF

Language: Spanish
References: 21
Page: 106-117
PDF size: 96.34 Kb.


ABSTRACT

Introduction. Testis cancer is the most common cancer among 15-35 years. Chemotherapy decrease mortality. Non seminomatous with teratoma constitute 55-80% and pure teratoma 2-5% of all. Treatment in advance stage is established but exists controversy in I. Objective. To know the survival in non seminomatous germ cells carcinoma with teratoma. Association between percentage of teratoma in testis cancer with recurrence, progression or death by stage and treatment. Material and method. Descriptive study, open, observational, ambispective. We include all non seminomatous testis cancer with teratoma treated since 1989-2003. We analize multiple variable. Used descriptive statistics and survival analysis by Kaplan Meier, Long-rank and Cox. A p = ≤ 0.05 was significant. Results. Fourty seven patients. Average age 25 years, seven with criptorquidia. Seven pure teratoma. 26 in stage I without recurrence. Twenty one in II or more. Eleven death, one in IB and 10 in IIA or greater. Advances stages, therapeutics chemotherapy and second line have more mortality (p = ‹ 0.05). Conclusions. Stage I can be continued with stric survillance. Advance stages have high risk of death.


REFERENCES

  1. Walsh. Campbell’s Urology. 8th ed. Ed. Suanders; 2002.

  2. Hamdy, Baster, Neal, Catalona. Management of Urologic Malignancies. Churchill Livingstone 2002.

  3. Carroll P. Urol Clin North Am 1998; 25(3).

  4. Ross K. Prepuberal testis tumor. Reviews in Urology 2004; 6(1): 11-8.

  5. Ulbright. Gonadal Teratomas: A review and speculation. Advances in Anatomic Pathology 2004; 11(1): 10-23.

  6. Shukla, Woodard, Carr, Huff, Canning, Zderic, Kolon, Snyder. Experience with testis sparing surgery for testicular teratoma. J Urol 2004; 171: 161-3.

  7. Beck, Foster, Bihrle, Ulbright, Koch, Wahle, Einhorn, Donohue. Teratoma in the orchiectomy specimen and volume of metastasis are predictors of retroperitoneal teratoma in post-chemotherapy nonseminomatous testis cancer. J Urol 2002; 168: 1402-4.

  8. Porcaro, Antoniolli, Martignoni, Brunelli, Curti. Adult primary teratoma of the testis: Report on 5 cases in clinical stage I disease. International Urology and Nephrology 2001; 33(4): 657-9.

  9. Axel H. Clinical stage I nonseminomatous testicular germ-cell tumors: Surgery or watchful waiting, still an issue? Current Opinion in Urology 2002; 12: 427-30.

  10. 10.Nicolai, Pizzocaro. A surveillance study of clinical stage I nonseminomatour germ cell tumors of the testis: 10 year followup. J Urol 1995; 154(3): 1045-9.

  11. 11.Hollins, Thomas, Lanigan, Dahar, Jodrell, Kaye, Kirk. Retroperitoneal surgery: Its wider role in the management of malignant teratoma. British J Urol 1996; 77(4): 571-6.

  12. 12.Sharir, Jewett, Sturgeon, Moore, Warde, Catton, Gospodarowicz. Progression detection of stage I nonseminomatous testis cancer on surveillance: Implications for the followup protocol. J Urol 1999; 161: 472-6.

  13. 13.Heidenreich, Judd, David, Mostofi, Engelmann. The role of retroperitoneal lymphadectomy in mature teratoma of the testis. J Urol 1997; 157(1): 160-3.

  14. Rabbani, Farivar-Mohseni, Leon, Motzer, Bosl, Sheinfeld. Clinical outcome after retroperitoneal lymphadenectomy of patients with pure testicular teratoma. Urology 2003; 62(6): 1092-6.

  15. 15 Comiter, Kibel, Richie, Nucci, Renshaw. Postic features of teratomas with malignant transformation: A clinicopathological study of 21 cases. J Urol 1998; 159(3): 859-63.

  16. 16.Chang, Sheinfeld. Clinical stage I nonseminomatous germ cell tumors: Treatment options. Aua Updates Series. Vol XX. 2001.

  17. 17.Hernández, Calderón. Infiltración vascular y carcinoma embrionario como factores pronósticos en cáncer de testículo no seminomatoso. Experiencia en el Hospital General Dr. Manuel Gea González. Rev Mex Urol 2001; 61(1): 16-20.

  18. 18.Registro Histopatológico de Neoplasias Malignas de México. 2000.

  19. 19.De Riese, Albers, Walker, Ulbright, Crabtree, Reister, Foster, Donohue. Predictive parameters of biologic behavior of early stage nonseminomatous testicular germ cell tumors. Cancer 1994; 74: 1335.

  20. 20.Albers, Ulbright, Albers, Miller, Orazi, Crabtree, Baniel, Reister, Sidner, Foster, Donohue. Tumor proliferative activity is predictive of pathological stage in clinical stage. A nonseminomatous testicular germ cell tumors. J Urol 1996; 155: 579-86.

  21. 21.Simmonds, Lee, Theaker, Tung, Smart, Mead. Primary pure teratoma of the testis. J Urol 1996; 155(3): 939-42.




2020     |     www.medigraphic.com