2005, Number 6
<< Back Next >>
Med Int Mex 2005; 21 (6)
Malignant schwannoma in the upper back region and right shoulder. A report of a case
Muñoz CJG, Orea ED, Sierra DCG, Molina CHR, Aboharp HZ, Mauro IJY
Language: Spanish
References: 18
Page: 524-528
PDF size: 154.70 Kb.
ABSTRACT
Malignant peripheral nerve tumor, also known as malignant neurogenic sarcoma, arise on Schwann cells and is usually associated to neurofibromatosis type 1 and 2. The most common location is on the extremities and is more frequent in males in middle age. The malignant schwannoma is an uncommon tumor and represents less than 1% in thoracic members, proportion that increases to 7% in children. Symptoms depend on the involved nerve. We present a case of a 24 years old woman, whose initial symptoms started ten months before her admission, with increase of volume in the upper back region and in the right shoulder, with slow and progressive growth, as well as with pain. The ultrasound and computerized tomography scan was performed; soft tissue tumor was the diagnosis of the biopsy, the histological result was malignant schwannoma.
REFERENCES
Weiss Sh, Goldblum J. Enzinger and Weiss’s soft tissue tumors. 4th ed. 2001;pp:1209-63.
Sternberg SS, Antonioli DA. Diagnostic surgical pathology. 3th ed. 1999;pp:185-8.
Cotran SR, Kumar V, Collins T. Patología estructural y funcional. 6a ed. México: McGraw-Hill, 2000;pp:1401-3.
Rinaldi E. Neurilemomas and neurofibromas of the extremity. J Hand Surg 1996;1:1153-6.
Greager JA, Reichard KW. Malignant schwannoma of the head and neck. Am J Surg 1992;163:440-2.
Sharma RR, Pawar SJ, Netalkar AS. Schwannoma of the suprascapular nerve presenting with neuralgia: case report and review of the literature. J Clin Neurosci 2001;1:60-63.
Hostales F, Pérez-Vallés A. Presentación de un caso de tumor maligno de la vaina del nervio periférico de localización superficial. Rev Esp Patol 1998;31:269-73.
Rosai J, Ackerman LV. Surgical pathology. 8th ed. New York: Mosby, 1995;pp:2041-53.
Ducatman BS, Scheithauer BW. Postirradiation neurofibrosarcoma. Cancer 1983;51:1028-33.
Koga T, Iwasaki H, Ishiguro M. Frequent genomic imbalances in chromosomes 17,19 and 22q in peripheral nerve sheath tumors detected by comparative genomic hybridization analysis. J Pathol 2002;197:98-107.
Barth H, Warzok R. Malignant neurinoma of the suprascapular nerve. Zentralbl Neurochir 1990;51:197-200.
Antoch G, Egelhof T, Korfee S. Recurrent schwannoma: diagnosis with PET/CT. Neurology 2002;59:1240-1.
Ferner RE, Gutmann DH. International Consensus Statement on Malignant Peripheral Nerve Sheath in Neurofibromatosis 1. Cancer Res 2002;62:1573-7.
Ducatman BS, Scheithauer BW. Malignant peripheral nerve sheath tumors with divergent differentiation. Cancer 1984;54:1049-57.
Younsen SA, Colby TV, Urich H. Malignant epithelioid schwannoma. Cancer 1985;55:2799-803.
Jimenez-Heffernan JA, Lopez-Ferrer P. Cytologic features of malignant peripheral nerve sheath tumor. Acta Cytol 1998;28:175-83.
Atkinson BK, Silverman JF. Atlas de dificultades diagnósticas en citopatología. Madrid: Harcourt, 2000;pp:482-96.
Weidner N. The difficult diagnosis in surgical pathology. Philadelphia: Saunders, 1996;pp:709-12.