2016, Number 6
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Acta Pediatr Mex 2016; 37 (6)
Comparative efficacy trial between two types of diapers for the prevention and treatment of diaper dermatitis
Sáez de Ocariz-Gutiérrez MM, Díaz-García L, Contreras-Verduzco FA, Narváez-Rosales V, Solís-Ortiz D, Greenawalt-Rodríguez S, Espinosa-Padilla S, Orozco-Covarrubias L
Language: Spanish
References: 27
Page: 310-321
PDF size: 674.27 Kb.
ABSTRACT
Background: To maintain the integrity of the skin in the area
covered by a diaper is a goal in order to avoid the development of
diaper dermatitis (DD).
Objetive: To compare the efficacy between two types of diapers
to prevent or treat DD.
Patients and Method: Clinical randomized trial in which infants
from 6 to 12 months of age, with or without DD, who used either
Huggies UltraConfort
™ or BBTips
™, were included. The presence or
absence of DD and the diapers’ efficacy evaluation by the physician
and the keeper were documented. Statistical analysis included uni
and bivariate analyses.
Results: In the group without DD, 68 infants with a mean age of
8.54 ± 2.09 months were evaluated. Seventy-two percent had had previous
events of DD. Fourteen infants developed DD. The comparison
between both types of diaper showed that BBTips
™ had a superior
efficacy over Huggies UltraConfort
™. In the group with DD, 66 patients
with a mean age of 8.65 ± 2.4 months were evaluated. Eighty-eight
percent had had previous events of DD. Fifty-three percent of the DD
had resolved by day 15, and 88% by day 30. The comparison between
both types of diapers did not show significant differences in efficacy.
Conclusions: BBTips
™ was superior to Huggies UltraConfort
™
for the prevention of DD. Both types of diapers had a similar efficacy
for the treatment of DD.
REFERENCES
Odio M, Friedlander SF. Diaper dermatitis and advances in diaper technology. Curr Opin Pediatr. 2000;12(4):342-6.
Berg RW. Etiology and pathophysiology of diaper dermatitis. Adv Dermatol. 1988;3:75-90.
Adam R. Skin care of the diaper area. Pediatr Dermatol. 2008;25:427-33.
Berg RW. Etiology and pathophysiology of diaper dermatitis. Adv Dermatol. 1988;3:75-98.
Atherton DJ. The aetiology and management of irritant diaper dermatitis. J Euro Acad Dermatol Venereol. 2001;15(Suppl):1-4.
Li CH, Zhu ZH, Dai YH. Diaper dermatitis: a survey of risk factors for children aged 1-24 months in China. Int Med Res. 2012;40(5):1752-60.
Adalat S, Wall D, Goodyear H. Diaper dermatitis-frequency and contributory factors in hospital attending children. Pediatr Dermatol. 2007;24(5):483-8.
Philipp R, Hughes A, Golding J. Getting to the bottom of nappy rash. ALSPAC Survey Team. Avon Longitudinal Study of Pregnancy and Childhood.Br J Gen Pract. 1997;47(421):493-7.
Jordan WE, Lawson KD, Berg RW, Franxman JJ, Marrer AM. Diaper dermatitis: frequency and severity among a general infant population. Pediatr Dermatol. 1986;3(3):198-207.
Langoen A, Vik H, Nyfors A. Tidsskr Nor Naegeforen. Diaper dermatitis. Classification, occurrence, causes, prevention and treatment. 2003;113(14):1712-5.
Levin S. History of medicine-diapers. S Afr Med J. 1970;44:256-63.
Campbell RL. Clinical tests with improved disposable diapers. Pediatrician. 1987;14Suppl 1:34-8.
Lane AT, Rehder PA, Helm K. Evaluation of diapers containing absorbent gelling material with conventional disposable diapers in newborn infants. Am J Dis Child. 1990;144:315-8.
Odio MR, O'Connor RJ, Sarbaugh F, Baldwin SC. Continuous topical administration of a petrolatum formulation by a novel disposable diaper. Effect on skin surface microtopography. Pediatric Dermatol. 2000;200:232-7.
Erasala GN, Merlay I. Romain G. Evolution of disposable diapers and reduction of diaper dermatitis. Arch Pediatr. 2007;14(5):495-500.
Baldwin S, Odio MR, Haines SL, O'Connor RJ, Englehart JS, Lane AT. Skin benefits from continuous topical administration of a zinc oxide/petrolatum formulation by a novel disposable diaper. J Eur Acad Dermatol Venereol. 2001;15(Suppl 1):5-11.
Panahi Y, Sharif MR, Sharif A, Beiraghdar F, Zahiri Z. A randomized comparative trial on the therapeutic efficacy of topical aloe vera and calendula officinalis on diaper dermatitis in children. Scientifc World Journal 2012. Article ID 810234, 5 pages doi:10.1100/2012/810234.
Davis JA, Leyden JJ, Grove GL ,Raynor WJ. Comparison of disposable diapers with fluff absorbent and fluff plus absorbent polymers: Effects on skin hydration, skin pH, and diaper dermatitis. Pediatric Dermatol. 1989;6(2):102-8.
Estudio de Calidad. Pañales Desechables. La Misión Antiescurrimiento en Revista del Consumidor. 2011. http:www.revistadelconsumidor.gob.mx/wp-content/ uploads/2011/10/estudio-panales.pdf.
Lwanga SK, Lemeshow S. Sample size determination in health studies. A practical manual. Geneva: World Health Organisation, 1991.
Scheinfeld N. Diaper dermatitis: A review and brief survey of eruptions of the diaper area. Am J Clin Dermatol 2005;6:273-81.
Ward DB, Fleischer AB Jr, Feldman SR, Krowchuk DP. Characterization of diaper dermatitis in the United States. Arch Pediatr Adolesc Med 2000;154(9):943-6.
Bound JP. Thrush napkin rashes. BMJ 1956;1:782-4.
Shin HT. Diaper dermatitis that does not quit. Dermatol Therapy 2005;18:124-35.
Munz D, Powell KR, Pai CH. Treatment of candida diaper dermatitis: a double-blind placebo-controlled comparison of topical nystatin with topical plus oral nystatin. J Pediatr. 1982;101:1022-5.
Koblenzer PJ. Diaper dermatitis: an overview. ClinPediatr 1973;12:386-92.
Baer EL, Davies MW, Easterbrook KJ. Disposable nappies for preventing napkin dermatitis in infants. Cochrane Database Syst Rev. 2006; 19;(3):CD004262.