2016, Number 1
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Arch Inv Mat Inf 2016; 8 (1)
Prevalence of hemoderivatives transfusions in newborns
Bobadilla MPV, Suárez VDE, Reyes BME
Language: Spanish
References: 42
Page: 23-31
PDF size: 106.89 Kb.
ABSTRACT
Introduction: Blood transfusion in newborns is common because of the increase of survival in newborns in the neonatal intensive care units. The literature reports from 8% to 20% needing blood transfusion.
Objective: Determine the prevalence of blood transfusion in newborn in the Hospital de
Ginecología y Obstetricia, of the
Instituto Materno Infantil del Estado de México from October 2014 to October 2015.
Material and methods: This is a descriptive, prospective, longitudinal study from a sample of 216 newborns of the neonatology service, non probabilistic consecutive cases type. The statistical analysis was performed with descriptive statistics.
Results: The prevalence of blood transfusion in our institution was 10%. Of the 216 patients included 54% were preterm infants (n = 117). The male gender was predominant in 61% (n = 136). The average hospital stay of 23 days. The main neonatal pathology was infectious disease area (n = 92) in 43%. In the follow-up period 436 transfusions were reported, the most common type of blood product was erythrocyte concentrate 50% (n = 218). The average of blood products administered were 2. Compliance for administration of blood products according to clinical practice guidelines were 69% for red cell concentrates (n = 150), while for fresh frozen plasma (n = 88) with 90%, nevertheless 81% (n = 97) of platelet concentrates had no indication. No adverse events were reported.
Conclusion: The prevalence of blood transfusion in patients of our institution is not different from that reported in the literature.
REFERENCES
Jiménez SA, Gini S, Echeverría O, Lemir ZMO. Guía para uso apropiado de componentes sanguíneos en pacientes pediátricos, Pediatr (Asunción), 2007; 34 (1): 46-68.
Restrepo CN. Manejo de componentes sanguíneos en recién nacidos, CCAP, 2013; 12 (2): 59-69.
Cloherty JP, Eichenwald EC, Hansen AR, Stark AR. Manual de neonatología, 7a ed. Estados Unidos: Lippincott Williams & Wilkins; 2012. p. 529.
Buys MC. Transfusiones sanguíneas y sus derivados en la práctica neonatal: enfoque clínico, Hematología, 1997; 1 (3): 91-94.
Folatre BI, Kuschel BC, Marín HF. Transfusiones de glóbulos rojos en recién nacidos de muy bajo peso de nacimiento, Rev Chil Pediatr, 2014; 85 (3): 298-303.
López CC, Eguigurems ZI, Valencia SG, Chang YA, Rodríguez WM. Factores asociados a la transfusión de sangre en neonatos críticamente enfermos, Rev Mex Ped, 2003; 70 (1); 10-13.
Del Pozo A. Transfusión en neonatología, Rev Hosp Mat Infant Ramón Sardá, 2009; 28 (2): 86-96.
Cortés BA. Medicina transfusional: evolución de una disciplina, Colomb Med, 1999; 30 (1): 3-4.
Salvatella FMJ. Antecedentes históricos de la medicina transfusional, Rev Mex Med Tran, 2008; 1 (1): 7-9.
Grispan S. Grupos sanguíneos ABO y Rh, Rev Médica Hondur, 1983; 51: 103-108.
Tonse NK. Historical perspectives: cured by the blood: the story of the first neonatal blood transfusion, Neo Reviews, 2006; 7 (2): e67-e68.
Tortosa-Pinto P, Tribak M, Uberos J. Transfusión de hemoderivados en pacientes pediátricos, Bol SPAO, 2012; 6 (3): 83-92.
Arca G, Carbonell-Estrany X. Anemia neonatal, AEPED, 2008; 37: 362-371.
Instituto Nacional de Perinatología Isidro Espinosa de los Reyes. Normas y procedimientos de neonatología 2015, 5a ed. México: Intersistemas; 2015. p. 184-187.
Manual CTO de medicina y cirugía: Hematología, 5a ed. Madrid: CTO Medicina; 2003. p. 3-5.
Nassin ML, Lapping-Carr G, de Jong JL. Anemia in the neonate: the differential diagnosis and treatment, Pediatric Ann, 2015; 44 (7): 159-163.
Henry E, Christensen RD, Sheffield MJ, Eggert LD, Carroll PD, Minton SD et al. Why do four NICUs using identical RBC transfusion guidelines have different gestational age-adjusted RBC transfusion rates?, J Perinatol, 2015; 35 (2): 132-136.
Catálogo maestro de guías de práctica clínica IMSS 540-12. Guía de referencia rápida: tratamiento de la anemia del prematuro, México: Secretaría de Salud; 2012. pp. 1-8.
Hensch LA, Indrikovs AJ, Shattuck KE. Transfusion in extremely low-birth-weight premature neonates: current practice trends, risks, and early interventions to decrease the need for transfusion, Neo Reviews, 2015; 16 (5): e287-e292.
Rodríguez FA, Solís SG, Ballesteros GS, Llaneza RJ, Lagunilla HL, Pérez MC. Extracciones y transfusiones en el recién nacido pretérmino, An Esp Pediatr, 1998; 49 (1): 55-59.
Lönnerdal B, Georgieff MK, Hernell O. Developmental physiology of iron absorption, homeostasis, and metabolism in the healthy term infant, J Pediatr, 2015; 167 (4 Suppl): S8-S14.
James L, Greenough A, Naik S. The effect of blood transfusion on oxygenation in premature ventilated neonates, Eur J Pediatr, 1997; 156 (2): 139-141.
Kabra NS. Blood transfusion in preterm neonates, Arch Dis Child Fetal Neonatal Ed, 2003; 88 (1): F78.
Ortiz P, Mingo A, Lozano M, Vesga MA, Grifols JR, Castrillo A et al. Guía sobre la transfusión de componentes sanguíneos. Conferencia de consenso, Med Clin (Barc), 2005; 125 (10): 389-396.
Abdelghaffar S, Mansi Y, Ibrahim R, Mohamed D. Red blood transfusion in preterm infants: changes in glucose, electrolytes and acid base balance, Asian J Transfus Sci, 2012; 6 (1): 36-41.
Seidel D, Bläser A, Gebauer C, Pulzer F, Thome U, Knüpfer M. Changes in regional tissue oxygenation, saturation and desaturations after red blood cell transfusion in preterm infants, J Perinatol, 2013; 33 (4): 282-287.
Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ et al. Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants, Pediatrics, 2005; 115 (6): 1685-91.
Kirpalani H, Whyte RK, Andersen C, Asztalos EV, Heddle N, Blajchman MA et al. The premature infants in need of transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants, J Pediatr, 2006; 149 (3): 301-307.
Orozco RDP, Zamorano JCA, Iglesias LJ, Bernárdez-Zapata I. Transfusión de concentrado eritrocitario asociado a enterocolitis necrosante en recién nacidos pretérmino, An Med (Mex), 2014; 59 (4): 261-266.
García-Graullera MG, Cordero-González G, Romero-Escriba AL, Guzmán-Moreno VA, Salinas-Ramírez V, Fernández-Carrocera LA. Sobrecarga de hierro y enfermedad hepática en recién nacidos sometidos a transfusiones de concentrados eritrocitarios, Perinatol Reprod Hum, 2003; 17 (3): 155-159.
Gupta AK, Kumari S, Shingal A, Bahl A. Neonatal thrombocytopenia and platelets transfusion, Asian J Transfus Sci, 2012; 6 (2): 161-164.
Sallmon H, Gutti RK, Ferrer-Marin F, Liu ZJ, Sola-Visner MC. Increasing platelets without transfusion: is it time to introduce novel thrombopoietic agents in neonatal care?, J Perinatol, 2010; 30 (12): 765-769.
Martín-Álvarez E, Hurtado-Suazo JA, Peña-Caballero M, Moreno-Galdó MF, Oyonarte-Gómez S. Transfusión de plaquetas en el recién nacido, Acta Pediatr Esp, 2010; 68 (10): 487-492.
Baer VL, Lambert DK, Schmutz N, Henry E, Stoddard RA, Miner C et al. Adherence to NICU transfusion guidelines: data from a multihospital healthcare system, J Perinatol, 2008; 28 (7): 492-497.
Christensen RD. Platelet transfusion in the neonatal intensive care unit: benefits, risks, alternatives, Neonatology, 2011; 100 (3): 311-318.
Chalmers EA. Neonatal coagulation problems, Arch Dis Child Fetal Neonatal Ed, 2004; 89 (6): F475-F478.
Tarud GG, Prieto RP, Vives PR. Hemoderivados en recién nacidos y niños, Barraquilla, Colombia: Ediciones Uninorte; 2008. pp. 1-3.
Escolan-Rodezno K, Eguigurems-Zamora I. Transfusión de componentes sanguíneos en el servicio de recién nacidos del Hospital Escuela: perfil epidemiológico y seguimiento de los estándares internacionales para su uso, Hond Ped, 2004; 24 (1): 11-16.
Viejo A, Ercoreca L, Canales MA. Hemoderivados, An Pediatr Contin, 2009; 7 (1): 24-28.
Martínez-García JJ, Ochoa-Espinoza R, Ríos-Osuna M, León-Sicarios N. Prevalencia de transfusiones de concentrado eritrocitario en una unidad de terapia intensiva pediátrica, Paed Méx, 2008; 1: 1.
Hubner GM, Nazer HJ, Cifuente OL. Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile, Rev Med Chile, 2001; 129 (5): 509-514.
Roseff SD. Neonatal transfusion practice: should or policies mature with our patients? Transfusion 2011; 51 (5): 908-913.