Pérez PZ, Castillo PA, Moreno RM, Hernández FY, Casas AX

Language: Spanish
References: 16
Page: 465-473
PDF size: 99.47 Kb.

ABSTRACT

Objective: to describe the association of clinical and epidemiological aspects with the microbiological results of patients with infectious keratitis, who were admitted to the corneal service of "Ramon Pando Ferrer" Cuban Institute of Ophthalmology in the period of 2010 to 2014.
Methods: cross-sectional, descriptive and observational study of 39 eyes. The analyzed variables were age, sex, time of progression, previous antibiotic treatment, predisposing factors and agreement of the empirical treatment. Summary measures for qualitative and quantitative variables; non-parametric Fisher´s exact probability test, Pearson´s Chi square test, and Mann Whitney's U test.
Results: in the bacterial isolates, 42.3 % of patients were younger than 30 years; 53.8 % were females and average time of progression of disease was 7 days. The predisposing factors were previous eye disease (23.1 %), use of contact lenses (30.8 %) and systemic diseases (11.5 %). Regarding mycotic isolates, patients aged over 69 years (46.5 %), males (92.3 %), average time of progression of 14.5 % and history of non surgical ocular trauma (15.4 %) predominated. The corneal perforation occurred in 7.7 % of bacterial infection whereas 15.4 % developed descemetocele and 23.1 % corneal perforation in the mycotic infection group. Penetrating keratoplasty was performed in 30.8 % of patients.
Conclusions: bacterial isolates were more frequent in young female patients with a history of previous ocular diseases and contact lenses whereas mycotic etiology was more commonly observed in males over 60 years and history of non surgical corneal trauma.

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