2016, Number 4
Nefropatía crónica grado 5 multicomplicada secundaria a hiperoxaluria primaria. Valor del diagnóstico etiológico
Language: Spanish
References: 10
Page: 59-66
PDF size: 883.17 Kb.
ABSTRACT
A young patient of African origin is presented, with previous history of urinary calcull observed at the age of 10 years and recurrent urinary tract infections and severe acute pyelonephritis; seven years later he arrived at stage 5 of the chronic kidney disease without nephrology monitoring. He started therapy with automated peritoneal dialysis and then hemodialysis. He received renal transplant of alive related donor that failed the tenth day in the context mediated by antibody rejection and evidence of crystals of calcium oxalate in the renal parenchyma and urinary spaces that confirmed the diagnosis of primary hyperoxaluria. Returned to periodical hemodialysis, he is exposed to a liver graft donated by another sister, with adequate recovery. He was admitted at four months for sepsis, giant abscess of the anterior abdominal wall, cerebral infarction, shock and death. It is important to establish the etiological diagnosis of the underlying nephropathy to decide the appropriate treatment of therapy.REFERENCES
Martín M, Martín Reyes G, Torres de Rueda A, Toledo Rojas R, Jironda C, García I, et al. Hiperoxaluria primaria de diagnóstico tardío en paciente joven con insuficiencia renal crónica avanzada. Nefrología (Madrid)[Internet]. 2011 [citado 12 Abr 2015];31(2):227-9. Disponible en: http://www.revistanefrologia.com/es-publicacion-nefrologia-articulo-hiperoxaluria-primaria-diagnostico-tardio-paciente-joven-con-insuficiencia-renal-cronica-X021169951105154X
Cochat P, Hulton SA, Acquaviva C, Danpure CJ, Daudon M, De Marchi M, et al. Primary hiperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment. Nephrol Dial Transplant [Internet]. 2012 [citado 12 Abr 2015];27(5):1729-36. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/22547750
Nair P, Al-Otaibi T, Nampoory N, Al-Qabandi W, Said T, Halim MA, Gheith O. Combined liver and kidney transplantation in primary hyperoxaluria: a report of three cases and review of the literature. Saudi J Kidney Dis Transpl [Internet]. 2013 [citado 12 Nov 2015];24(5):969-75. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24029263