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2016, Number 3

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Rev Hematol Mex 2016; 17 (3)

Optimal diagnostic methods in patients with acute myelogenous leukemia

Cruz-Santana LC, Garza-Ledezma MA, Méndez-Ramírez N, Cárdenas-Araujo D, Gómez-Almaguer D

Language: Spanish
References: 35
Page: 187-194
PDF size: 352.72 Kb.


ABSTRACT

Acute myeloid leukemia is a heterogeneous clonal disorder originated from the hematopoietic progenitor cells and is currently considered the most common acute leukemia in adults. Median age at diagnosis among white population from the USA is 67 years. However, the median age in Mexico has been reported to be between 32-44 years. Diagnosis can be suspected by the clinical manifestations of the patients or by the results of a complete blood account. Nevertheless, a series of studies is required to confirm the diagnosis of acute myeloid leukemia. In the last decades, immunophenotyping by flow cytometry, and cytogenetics and molecular markers have acquired great importance and have become tools for diagnosis and follow-up, as well as for prognostic evaluation for acute myeloid leukemia.


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