Pérez CR

Language: Spanish
References: 44
Page: 165-169
PDF size: 59.25 Kb.

ABSTRACT

Hypoperfusion lead to hypoxia and decrease of adenosine triphosphate (ATP) levels during sepsis and shock. Si-multaneously the requirement of energy for protection of cells is increased. An adequate restoration of intravascular volume and arterial pressure is not enough to avoid the cellular damage during the hypotension period and the development of multiple organ failure may be observed. In this issue are reviewed the effects of ATP on the cellular function and the clinical results with the use of this in the treatment of hypoperfusion. ATP-Mg.Cl₂ can increase the cardiac output and the coronary flow and decrease the oxygen consumption, without arterial hypotension.

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