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2016, Number 4

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Gac Med Mex 2016; 152 (4)

False positive result in mammography and its association with the presence of obesity: a case-control study

Castro-Ibarra M, Menchaca-Díaz R, Cabrales-Ruvalcaba JJ, Luna-V GRA

Language: Spanish
References: 19
Page: 503-507
PDF size: 686.25 Kb.


ABSTRACT

Objective: To analyze the association between a false positive result in mammography and obesity, inside the breast cancer early detection program in women affiliated to the Institute of Security and Social Services for Government and Municipality workers of the State of Baja California (ISSSTECALI). Material and methods: A case-control, retrospective study was done in women affiliated to ISSSTECALI to whom a mammography was performed between 2009 and 2012. Women with a false positive result in mammography were included as cases. Controls were women with a true negative result in mammography. Three controls were randomly selected for each case. Obesity was established with the body mass index (BMI) consigned in the woman’s clinical file. Age and estrogen replacement therapy were included as co-variables. Results: Seventy nine cases were identified and 237 controls were included. Obesity was observed in 54.4% of cases and in 41.3% of controls (odds ratio: 1.69; 95% confidence interval for odds ratio: 1.01-2.82; p value: 0.043). A logistic regression model including covariables maintained the observed association (p = .044). No association was found with analyzed co-variables. Conclusions: A false positive result in mammography was associated with the presence of obesity.


REFERENCES

  1. Romero-Figueroa MS, Santillán-Arreygue L, Olvera-Hernández PC, Morales- Sánchez MA, Ramírez-Mendiola VL. Frecuencia de factores de riesgo de cáncer de mama. Ginecol Obstet Mex. 2008;76(11):667-72.

  2. Aguilar-Cordero M, González-Jiménez E, García-López A, et al. Obesidad y su implicación en el cáncer de mama. Nutr Hosp. 2011;26(4):899-903.

  3. Elmore JG, Carney PA, Abraham LA, et al. The Association Between Obesity and Screening Mammography Accuracy. Arch Intern Med. 2004;164:1140-7.

  4. Gómez-Cámara A. Caracterización de pruebas diagnósticas. Medicine. 1998;7(104):4872-7.

  5. Banks E, Reeves G, Beral V, et al. Impact of use of hormone replacement therapy on false positive recall in the NHS breast screening programme: results from the million women study. BMJ. 2004;328:1291.

  6. Knaul FM, Nigenda G, Lozano R, Arreola-Ornelas H, Langer A, Frenk J. Cáncer de mama en México: una prioridad apremiante. Salud Publica Mex. 2009;51(2):S335-44.

  7. Encuesta nacional de salud y nutrición 2012 resultados nacionales. México: Instituto Nacional de Salud Pública; 2012.

  8. Elmore JG, Armstrong K, Lehman CD, Fletcher SW. Screening for breast cancer. JAMA: J Am Med Assoc. 2005;293(10):1245-56.

  9. Smith RA. Screening techniques. IARC. Handbooks of cancer prevention. 2002;7:25-46.

  10. Estadísticas a propósito del día mundial contra el cáncer. Datos nacionales. INEGI; 2011.

  11. Elmore JG, Barton MB, Moceri VM, Polk S, Arena PJ, Fletcher SW. Tenyear risk of false positive screening mammograms and clinical breast examinations. N Engl J Med. 1998;338(16):1089-96.

  12. Elmore JG, Carney PA, Abraham LA, et al. The association between obesity and screening mammography accuracy. Arch Intern Med. 2004;164(10):1140-7.

  13. DeFrank JT, Rimer BK, Bowling JM, Earp JA, Breslau ES, Brewer NT. Influence of false-positive mammography results on subsequent screening: do physician recommendations buffer negative effects? J Med Screen. 2012;19(1):35-41.

  14. Van der Steeg AF, Keyzer-Dekker CM, De Vries J, Roukema JA. Effect of abnormal screening mammogram on quality of life. Br J Surg. 2011;98(4):537-42.

  15. Brodersen J, Siersma VD. Long-term psychosocial consequences of false-positive screening mammography. Ann Fam Med. 2013;11(2):106-15.

  16. Njor SH, Olsen AH, Schwartz W, Vejborg I, Lynge E. Predicting the risk of a false-positive test for women following a mammography screening programme. J Med Screen. 2007;14(2):94-7.

  17. Lehman CD, White E, Peacock S, Drucker MJ, Urban N. Effect of age and breast density on screening mammograms with false-positive findings. AJR. Am J Roentgenol. 1999;173(6):1651-5.

  18. Salas D, Ibáñez J, Román R, et al. Effect of start age of breast cancer screening mammography on the risk of false-positive results. Prev Med. 2011;53(1-2):76-81.

  19. Laya MB, Larson EB, Taplin SH, White E. Effect of Estrogen Replacement Therapy on the Specificity and Sensitivity of Screening Mammography. J Natl Cancer Inst. 1996;88(10):643-9.




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