López-Sandoval JJ, Alfaro-Castellanos DE, Valle-Delgado E, Angulo-Castellanos E, García-Camarena H, Parra-O´connor S, González-Cortés LF, Villalobos-Lizardi JC, Álvarez-Mancilla LE, Aguirre-Jáuregui Ó, Yanowski-Reyes G, Santana-Ortiz R, Padilla-Muñoz H

Language: Spanish
References: 11
Page: 229-234
PDF size: 585.75 Kb.

ABSTRACT

Introduction. Total parenteral nutrition is used in patients with gastrointestinal abnormalities; nevertheless it has been associated to metabolic, infectious and mechanic complications. The main objective of this study is to investigate the main metabolic complications of total parenteral nutrition (TPN) in neonates at the extern neonatal intensive care unit (UCINEX).
Material and Methods. This is a transversal and analytic study. All neonates admitted to the ENICU at the Hospital Civil de Guadalajara Fray Antonio Alcalde who received TPN for more than 10 days were included. The study took place from January 2011 to December 2014. The following variables were analyzed: biophysical profile (gender, gestational age, weight at start and at the end of TPN), duration of TPN, type of catheter used, (peripheral percutaneous o central venous access) and biochemical data (blood count, renal function tests, lipid profile, electrolytes and liver tests). Data were processed using IBM SPSS program 20.0 version for Windows 7, Epidat from the Galicia Joint, and Panamerican Health Organization version 3.1, and Epi Info version 7.0 from the Atlanta CDC.
Results. The weight when NPT was started had a correlation of 89% with the weight at the end of it. In both groups central venous access was the most common administration route (76.1%). In both groups, the most common metabolic complication was cholestasis in 38% of the term newborns and 35.9% of the preterm newborns. The second most common was hyperglycemia with 38% and 28% respectively.
Conclusions. Complications associated to TPN were most frequent among preterm infants. In the Extern Neonatal Intensive Care Unit, the use of TPN has a positive impact in growth and development of newborns.

REFERENCES

1. AG, Jiménez Uribe, et al. Relación entre el soporte nutricion enteral, parenteral o mixto y la evolución nutricioal de neonatos prematuros en la unidad de cuidados intensivos. Revista Médica MD, 2014, Vol. 5. 2007-8188.

2. L. Garzón, et, al. Colestasis asociada a la nutrición parenteral prolongada en el periodo neonatal: posible eficacia del ácido ursodesoxicólico. El Servier, 2009, Vol. 70. 1695-4033.

3. Koletzco, Berthold, et al. Guidelines of Paedriatric Parenteral Nutrition of the European Society of Paediatria Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN). Journal of Pediatric Gastroenterology and Nutrition, Noviembre de 2005, Vol. 41. 0277-2116.

4. Nutrición parenteral en pediatría. Secretaria de Salud. Gobierno Federal.Mexico : CENETEC, 2008. SSA-121-08.

5. Martín CR, et al. Nutritional practices and growth velocity in the first month of life in the extremely low gestational age newborns. Pediatrics. 2009;124(2):649- 657.

6. Ruesch, et al. Complications of central venous catheters: Internal jugular versus subclavian acces- A systematic review. Lippincott Williams & Wilkins, 2002, Vol. 30. 0090-3493.

7. Rombo, et al. Factores asociados a complicaciones del uno de nutrición parenteral en recién nacidos prematuros. Revista de Investigación Clínica, Marzo - Abril de 2013, Revista de Investigación Clínica, Vol. 65, págs. 116-129. 0034-8376.

8. Silvia, et al. Complicaciones de la nutrición parenteral total en neonatos. Revista Mexicana de Pediatría, 2000, Vol. 67. 0035-0052.

9. Lapillonnes, et al. Current Practice for Parenteral Nutrition (glucose and calories) in neonatal intensive care units responding to the surveys. American Society for Nutrition, 2013, Vol. 143. 0022-3166.

10. A.S.P.E.N. Parenteral Nutrition Safety Consensus Recommendations. Journal of Parenteral and Enteral Nutrition, 2014, Vol. 38. 0148-6071.

11. Tapia-Rombo, et al. Factores asociados a complicaciones del uso de nutrición parenteral en recién nacidos prematuros Factores asociados a complicaciones del uso de nutrición parenteral en recién nacidos prematuros. Revista de Investigación Clínica i es c / Vol. 65, Núm. 2 / Marzo-Abril, 2013 / pp 116-129.