2016, Number 2
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Dermatología Cosmética, Médica y Quirúrgica 2016; 14 (2)
Basal cell carcinoma. Treatment with intralesional alfa 2b interferon
Vega GLG
Language: Spanish
References: 26
Page: 102-107
PDF size: 292.86 Kb.
ABSTRACT
Background: basal cell carcinoma is the most common cancer
and surgery is the treatment of choice. There are nonsurgical
options, such as intralesional alfa 2b interferon.
Objetive: the aim was to establish the safety and efficacy of
iINFα2b and report if the topography and morphology of the
lesion influence in the clinical response.
Methods: we studied 78 patients at Dermatology section in
a Hospital Vasco de Quiroga, issste, in the city of Morelia, Michoacán.
All patients included with either primary or recurrent
tumor, and treated with 2 million of iu of INFα2b intralesional
three times a week, with a total dosis of 18 000 000 ui.
Results: the global positive response was 84.6%, and the clinical
types, nodular and morpheaform, had a better response and
good aesthetic results.
Conclusions: infα2b is a safe and efficacious alternative
treatment of basal cell carcinoma, especially the nodular and
morpheaform types.
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